BRD-K01436366_-666_HT29_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

119 genes differentially expressed following the BRD-K01436366_-666_HT29_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABAT 4-aminobutyrate aminotransferase
ABHD6 abhydrolase domain containing 6
ACKR3 atypical chemokine receptor 3
ADCY9 adenylate cyclase 9
ADM adrenomedullin
ALDOC aldolase C, fructose-bisphosphate
APOB apolipoprotein B
BAG3 BCL2-associated athanogene 3
CACNA2D2 calcium channel, voltage-dependent, alpha 2/delta subunit 2
CADM1 cell adhesion molecule 1
CALM1 calmodulin 1 (phosphorylase kinase, delta)
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CIRBP cold inducible RNA binding protein
CLIC3 chloride intracellular channel 3
CSRP2 cysteine and glycine-rich protein 2
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
DNAJB6 DnaJ (Hsp40) homolog, subfamily B, member 6
DNAJC6 DnaJ (Hsp40) homolog, subfamily C, member 6
DSP desmoplakin
FEZ1 fasciculation and elongation protein zeta 1 (zygin I)
FGFR3 fibroblast growth factor receptor 3
GAS6 growth arrest-specific 6
GATA6 GATA binding protein 6
H2BFS H2B histone family, member S (pseudogene)
HIST1H1C histone cluster 1, H1c
HIST1H2AC histone cluster 1, H2ac
HIST1H2AE histone cluster 1, H2ae
HIST1H2BD histone cluster 1, H2bd
HIST1H2BF histone cluster 1, H2bf
HIST1H2BH histone cluster 1, H2bh
HIST1H2BK histone cluster 1, H2bk
HIST1H3H histone cluster 1, H3h
HIST3H2A histone cluster 3, H2a
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
HSD17B6 hydroxysteroid (17-beta) dehydrogenase 6
IDI1 isopentenyl-diphosphate delta isomerase 1
IER5 immediate early response 5
IGFBP5 insulin-like growth factor binding protein 5
INSIG1 insulin induced gene 1
ISG15 ISG15 ubiquitin-like modifier
JAG1 jagged 1
LPIN1 lipin 1
MIR22HG MIR22 host gene
MTSS1 metastasis suppressor 1
MYO1B myosin IB
NEBL nebulette
NNAT neuronatin
NRCAM neuronal cell adhesion molecule
ORM1 orosomucoid 1
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble)
PPP1R3C protein phosphatase 1, regulatory subunit 3C
RYBP RING1 and YY1 binding protein
SCGB2A2 secretoglobin, family 2A, member 2
SDC2 syndecan 2
SLC25A4 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4
SPOCK1 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1
STXBP1 syntaxin binding protein 1
SULF1 sulfatase 1
TIMP3 TIMP metallopeptidase inhibitor 3
TMSB15A thymosin beta 15a
TSHR thyroid stimulating hormone receptor
TSPAN13 tetraspanin 13
TUBA1A tubulin, alpha 1a
TUBB2A tubulin, beta 2A class IIa
TUFT1 tuftelin 1
TXNIP thioredoxin interacting protein

decreased expression

Symbol Name
ABCE1 ATP-binding cassette, sub-family E (OABP), member 1
ACSL5 acyl-CoA synthetase long-chain family member 5
ACTN1 actinin, alpha 1
ALOX5 arachidonate 5-lipoxygenase
B4GALT5 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5
BHLHE41 basic helix-loop-helix family, member e41
C1QBP complement component 1, q subcomponent binding protein
CA12 carbonic anhydrase XII
CDH6 cadherin 6, type 2, K-cadherin (fetal kidney)
CHL1 cell adhesion molecule L1-like
CXCL8 chemokine (C-X-C motif) ligand 8
DPH2 DPH2 homolog (S. cerevisiae)
IGHM immunoglobulin heavy constant mu
JADE2 jade family PHD finger 2
KDELR3 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3
KRT7 keratin 7, type II
LAPTM4B lysosomal protein transmembrane 4 beta
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1
LTF lactotransferrin
LY6E lymphocyte antigen 6 complex, locus E
MBNL2 muscleblind-like splicing regulator 2
MECOM MDS1 and EVI1 complex locus
MRPS2 mitochondrial ribosomal protein S2
MUC16 mucin 16, cell surface associated
MYC v-myc avian myelocytomatosis viral oncogene homolog
NUP62 nucleoporin 62kDa
PARP2 poly (ADP-ribose) polymerase 2
PFAS phosphoribosylformylglycinamidine synthase
PLAT plasminogen activator, tissue
PLBD1 phospholipase B domain containing 1
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit
PON2 paraoxonase 2
POU2AF1 POU class 2 associating factor 1
PPAP2C phosphatidic acid phosphatase type 2C
PPARG peroxisome proliferator-activated receptor gamma
PRR7 proline rich 7 (synaptic)
PUF60 poly-U binding splicing factor 60KDa
RCN1 reticulocalbin 1, EF-hand calcium binding domain
SPR sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase)
SRM spermidine synthase
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila)
TCERG1 transcription elongation regulator 1
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast)
TNFSF13 tumor necrosis factor (ligand) superfamily, member 13
TRIP6 thyroid hormone receptor interactor 6
TSKU tsukushi, small leucine rich proteoglycan
TSPAN8 tetraspanin 8
UBE2E3 ubiquitin-conjugating enzyme E2E 3
WFDC2 WAP four-disulfide core domain 2
ZNF512B zinc finger protein 512B