BRD-K01436366_-666_HA1E_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

133 genes differentially expressed following the BRD-K01436366_-666_HA1E_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADIRF adipogenesis regulatory factor
ALB albumin
ASS1 argininosuccinate synthase 1
ATF3 activating transcription factor 3
BAMBI BMP and activin membrane-bound inhibitor
BLNK B-cell linker
BTG1 B-cell translocation gene 1, anti-proliferative
BTG2 BTG family, member 2
BZW2 basic leucine zipper and W2 domains 2
C6 complement component 6
CALM1 calmodulin 1 (phosphorylase kinase, delta)
CCNG2 cyclin G2
CD24 CD24 molecule
COL1A1 collagen, type I, alpha 1
COL5A1 collagen, type V, alpha 1
CTH cystathionine gamma-lyase
CYB5R1 cytochrome b5 reductase 1
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1
DCAF10 DDB1 and CUL4 associated factor 10
DEPTOR DEP domain containing MTOR-interacting protein
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9
FABP4 fatty acid binding protein 4, adipocyte
FGFR3 fibroblast growth factor receptor 3
FLNA filamin A, alpha
FOXN3 forkhead box N3
GADD45B growth arrest and DNA-damage-inducible, beta
GAS1 growth arrest-specific 1
GC group-specific component (vitamin D binding protein)
GREM1 gremlin 1, DAN family BMP antagonist
H2BFS H2B histone family, member S (pseudogene)
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HIST1H1C histone cluster 1, H1c
HIST1H2BC histone cluster 1, H2bc
HIST2H2BE histone cluster 2, H2be
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
IDI1 isopentenyl-diphosphate delta isomerase 1
IER5 immediate early response 5
IGL immunoglobulin lambda locus
INSIG1 insulin induced gene 1
KCTD12 potassium channel tetramerization domain containing 12
KDM3A lysine (K)-specific demethylase 3A
KIAA0226L KIAA0226-like
KLF4 Kruppel-like factor 4 (gut)
LCN2 lipocalin 2
LGALS4 lectin, galactoside-binding, soluble, 4
MAN1A1 mannosidase, alpha, class 1A, member 1
MGEA5 meningioma expressed antigen 5 (hyaluronidase)
MSMO1 methylsterol monooxygenase 1
MYO1B myosin IB
NDRG1 N-myc downstream regulated 1
NEB nebulin
NPTX2 neuronal pentraxin II
ORC1 origin recognition complex, subunit 1
PAPSS1 3'-phosphoadenosine 5'-phosphosulfate synthase 1
PELI1 pellino E3 ubiquitin protein ligase 1
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
RGCC regulator of cell cycle
RGS2 regulator of G-protein signaling 2
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SHB Src homology 2 domain containing adaptor protein B
SPINK1 serine peptidase inhibitor, Kazal type 1
SPTAN1 spectrin, alpha, non-erythrocytic 1
SULF1 sulfatase 1
TCF4 transcription factor 4
TDO2 tryptophan 2,3-dioxygenase
THBS2 thrombospondin 2
TIMP3 TIMP metallopeptidase inhibitor 3
TOB1 transducer of ERBB2, 1
TRIL TLR4 interactor with leucine-rich repeats
TXNIP thioredoxin interacting protein
WIPI1 WD repeat domain, phosphoinositide interacting 1
ZFP36 ZFP36 ring finger protein

decreased expression

Symbol Name
ADGRE5 adhesion G protein-coupled receptor E5
ALCAM activated leukocyte cell adhesion molecule
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
APOD apolipoprotein D
ATF1 activating transcription factor 1
ATP6V0E2 ATPase, H+ transporting V0 subunit e2
AXL AXL receptor tyrosine kinase
B3GNT1
CALML5 calmodulin-like 5
CBR3 carbonyl reductase 3
CCDC86 coiled-coil domain containing 86
CCNE2 cyclin E2
CHI3L2 chitinase 3-like 2
CXCL14 chemokine (C-X-C motif) ligand 14
DKK1 dickkopf WNT signaling pathway inhibitor 1
EDN1 endothelin 1
EMP1 epithelial membrane protein 1
EMP3 epithelial membrane protein 3
FABP7 fatty acid binding protein 7, brain
FAM57A family with sequence similarity 57, member A
FOLR1 folate receptor 1 (adult)
FOSL1 FOS-like antigen 1
GLIPR1 GLI pathogenesis-related 1
HOXB2 homeobox B2
HOXB7 homeobox B7
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3
INTS3 integrator complex subunit 3
JADE2 jade family PHD finger 2
KEAP1 kelch-like ECH-associated protein 1
LPAR1 lysophosphatidic acid receptor 1
MET MET proto-oncogene, receptor tyrosine kinase
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
MMP7 matrix metallopeptidase 7
MOK MOK protein kinase
MT1F metallothionein 1F
NBN nibrin
NME4 NME/NM23 nucleoside diphosphate kinase 4
NMI N-myc (and STAT) interactor
OXTR oxytocin receptor
PLAC8 placenta-specific 8
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit
PTX3 pentraxin 3, long
QKI QKI, KH domain containing, RNA binding
RASA1 RAS p21 protein activator (GTPase activating protein) 1
RHOBTB3 Rho-related BTB domain containing 3
SFRP1 secreted frizzled-related protein 1
SLC39A8 solute carrier family 39 (zinc transporter), member 8
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6
SORBS3 sorbin and SH3 domain containing 3
SORD sorbitol dehydrogenase
STXBP2 syntaxin binding protein 2
SYNCRIP synaptotagmin binding, cytoplasmic RNA interacting protein
SYNGR1 synaptogyrin 1
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TFPI2 tissue factor pathway inhibitor 2
TGFBR3 transforming growth factor, beta receptor III
TM4SF1 transmembrane 4 L six family member 1
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TXNDC9 thioredoxin domain containing 9