BRD-K01292756_-666_HT29_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

23 genes differentially expressed following the BRD-K01292756_-666_HT29_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
CDK2AP2 cyclin-dependent kinase 2 associated protein 2
DDIT4 DNA-damage-inducible transcript 4
ELANE elastase, neutrophil expressed
HIST1H2BG histone cluster 1, H2bg
IFI6 interferon, alpha-inducible protein 6
INSIG1 insulin induced gene 1
MDK midkine (neurite growth-promoting factor 2)
NEU1 sialidase 1 (lysosomal sialidase)
NSDHL NAD(P) dependent steroid dehydrogenase-like
SQSTM1 sequestosome 1

decreased expression

Symbol Name
CCL4 chemokine (C-C motif) ligand 4
CPE carboxypeptidase E
CYR61 cysteine-rich, angiogenic inducer, 61
ERBB2 erb-b2 receptor tyrosine kinase 2
KCTD5 potassium channel tetramerization domain containing 5
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae)
MRPS2 mitochondrial ribosomal protein S2
MRPS30 mitochondrial ribosomal protein S30
PCCB propionyl CoA carboxylase, beta polypeptide
RGS2 regulator of G-protein signaling 2