BRD-K01121114_AT-MLPCN CSC-006_RMUGS_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

64 genes differentially expressed following the BRD-K01121114_AT-MLPCN CSC-006_RMUGS_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABLIM1 actin binding LIM protein 1
ADGRG2 adhesion G protein-coupled receptor G2
AGTR1 angiotensin II receptor, type 1
BIN1 bridging integrator 1
C3 complement component 3
CCL2 chemokine (C-C motif) ligand 2
CLU clusterin
CRTC3 CREB regulated transcription coactivator 3
DDIT4 DNA-damage-inducible transcript 4
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
FAM129A family with sequence similarity 129, member A
IER3 immediate early response 3
ITM2A integral membrane protein 2A
JUN jun proto-oncogene
KCNJ16 potassium channel, inwardly rectifying subfamily J, member 16
KDM5D lysine (K)-specific demethylase 5D
KLK5 kallikrein-related peptidase 5
KRT17 keratin 17, type I
MATN2 matrilin 2
MELK maternal embryonic leucine zipper kinase
MRPS2 mitochondrial ribosomal protein S2
MYC v-myc avian myelocytomatosis viral oncogene homolog
NEB nebulin
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NSDHL NAD(P) dependent steroid dehydrogenase-like
PALMD palmdelphin
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent)
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
PPAP2A phosphatidic acid phosphatase type 2A
PRKCQ protein kinase C, theta
PROM1 prominin 1
RBPMS RNA binding protein with multiple splicing
RPS4Y1 ribosomal protein S4, Y-linked 1
SFRP1 secreted frizzled-related protein 1
TESC tescalcin
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
TNFAIP3 tumor necrosis factor, alpha-induced protein 3

decreased expression

Symbol Name
C6ORF62 chromosome 6 open reading frame 62
CAPN2 calpain 2, (m/II) large subunit
CDC42 cell division cycle 42
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CRK v-crk avian sarcoma virus CT10 oncogene homolog
CXADR coxsackie virus and adenovirus receptor
FABP5 fatty acid binding protein 5 (psoriasis-associated)
GDPD5 glycerophosphodiester phosphodiesterase domain containing 5
GNS glucosamine (N-acetyl)-6-sulfatase
GPRC5A G protein-coupled receptor, class C, group 5, member A
IGFBP5 insulin-like growth factor binding protein 5
IGKC immunoglobulin kappa constant
IGL immunoglobulin lambda locus
JCHAIN joining chain of multimeric IgA and IgM
MAL mal, T-cell differentiation protein
MDFIC MyoD family inhibitor domain containing
NETO2 neuropilin (NRP) and tolloid (TLL)-like 2
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform
SELENBP1 selenium binding protein 1
SEPP1 selenoprotein P, plasma, 1
SLC26A2 solute carrier family 26 (anion exchanger), member 2
SMYD2 SET and MYND domain containing 2
TPD52 tumor protein D52
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
ZNF91 zinc finger protein 91