BRD-K00615600_Unable to generate chemical name O-4537-1_VCAP_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

96 genes differentially expressed following the BRD-K00615600_Unable to generate chemical name O-4537-1_VCAP_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ASCL1 achaete-scute family bHLH transcription factor 1
ASS1 argininosuccinate synthase 1
BEX4 brain expressed, X-linked 4
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
COL6A1 collagen, type VI, alpha 1
CORO1A coronin, actin binding protein, 1A
CPE carboxypeptidase E
DDC dopa decarboxylase (aromatic L-amino acid decarboxylase)
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
FJX1 four jointed box 1 (Drosophila)
FST follistatin
FXYD6 FXYD domain containing ion transport regulator 6
G0S2 G0/G1 switch 2
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
KRT23 keratin 23, type I
MMP10 matrix metallopeptidase 10
MUC16 mucin 16, cell surface associated
PLAU plasminogen activator, urokinase
PRR7 proline rich 7 (synaptic)
RBP1 retinol binding protein 1, cellular
RGS5 regulator of G-protein signaling 5
RNASE1 ribonuclease, RNase A family, 1 (pancreatic)
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
SLCO4A1 solute carrier organic anion transporter family, member 4A1
SMAD1 SMAD family member 1
SNX7 sorting nexin 7
SOX11 SRY (sex determining region Y)-box 11
SPARCL1 SPARC-like 1 (hevin)
THY1 Thy-1 cell surface antigen

decreased expression

Symbol Name
ADAM10 ADAM metallopeptidase domain 10
ADCY1 adenylate cyclase 1 (brain)
AHR aryl hydrocarbon receptor
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
AKR1C3 aldo-keto reductase family 1, member C3
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
ANPEP alanyl (membrane) aminopeptidase
ARL6IP1 ADP-ribosylation factor-like 6 interacting protein 1
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide
BASP1 brain abundant, membrane attached signal protein 1
C1ORF115 chromosome 1 open reading frame 115
CBR3 carbonyl reductase 3
CLDN18 claudin 18
CST3 cystatin C
CSTA cystatin A (stefin A)
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2
DUSP10 dual specificity phosphatase 10
ECI2 enoyl-CoA delta isomerase 2
FAM46C family with sequence similarity 46, member C
FOXO4 forkhead box O4
FXYD3 FXYD domain containing ion transport regulator 3
GALNT10 polypeptide N-acetylgalactosaminyltransferase 10
GATA2 GATA binding protein 2
GLRX glutaredoxin (thioltransferase)
GTPBP8 GTP-binding protein 8 (putative)
HES1 hes family bHLH transcription factor 1
HOXC6 homeobox C6
IGFBP6 insulin-like growth factor binding protein 6
KIAA0101 KIAA0101
KRT14 keratin 14, type I
KRT18 keratin 18, type I
LDLRAP1 low density lipoprotein receptor adaptor protein 1
LIMS1 LIM and senescent cell antigen-like domains 1
MAGED1 melanoma antigen family D1
MEGF9 multiple EGF-like-domains 9
MYO6 myosin VI
NNMT nicotinamide N-methyltransferase
NPY neuropeptide Y
NQO1 NAD(P)H dehydrogenase, quinone 1
NRIP1 nuclear receptor interacting protein 1
NRN1 neuritin 1
OSBPL8 oxysterol binding protein-like 8
PCTP phosphatidylcholine transfer protein
PIR pirin (iron-binding nuclear protein)
PRDX1 peroxiredoxin 1
PSD3 pleckstrin and Sec7 domain containing 3
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
SLC26A2 solute carrier family 26 (anion exchanger), member 2
SLC44A4 solute carrier family 44, member 4
SPDEF SAM pointed domain containing ETS transcription factor
STOM stomatin
TIMP1 TIMP metallopeptidase inhibitor 1
TM9SF3 transmembrane 9 superfamily member 3
TMEM255A transmembrane protein 255A
TMEM87A transmembrane protein 87A
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TOB1 transducer of ERBB2, 1
TOP2A topoisomerase (DNA) II alpha 170kDa
TPM1 tropomyosin 1 (alpha)
WDTC1 WD and tetratricopeptide repeats 1
ZMYND8 zinc finger, MYND-type containing 8