BRD-K00615600_Unable to generate chemical name O-4537-1_HT29_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

92 genes differentially expressed following the BRD-K00615600_Unable to generate chemical name O-4537-1_HT29_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACTA2 actin, alpha 2, smooth muscle, aorta
ACTG2 actin, gamma 2, smooth muscle, enteric
AGR2 anterior gradient 2
ATP8B1 ATPase, aminophospholipid transporter, class I, type 8B, member 1
CALD1 caldesmon 1
COL15A1 collagen, type XV, alpha 1
CTGF connective tissue growth factor
CTSK cathepsin K
DKK3 dickkopf WNT signaling pathway inhibitor 3
EPB41L2 erythrocyte membrane protein band 4.1-like 2
EPCAM epithelial cell adhesion molecule
F2RL1 coagulation factor II (thrombin) receptor-like 1
GATA3 GATA binding protein 3
GREB1 growth regulation by estrogen in breast cancer 1
HADHA hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit
HTR2B 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled
IGFBP6 insulin-like growth factor binding protein 6
ITM2C integral membrane protein 2C
JAG1 jagged 1
KRT19 keratin 19, type I
MGP matrix Gla protein
MMP12 matrix metallopeptidase 12
MMP3 matrix metallopeptidase 3
MYH11 myosin, heavy chain 11, smooth muscle
ORAI2 ORAI calcium release-activated calcium modulator 2
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PEG3 paternally expressed 3
PIR pirin (iron-binding nuclear protein)
PLIN2 perilipin 2
PMP22 peripheral myelin protein 22
RBP1 retinol binding protein 1, cellular
RGS10 regulator of G-protein signaling 10
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
TAGLN transgelin
TCFL5 transcription factor-like 5 (basic helix-loop-helix)
THBS1 thrombospondin 1

decreased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ANGPT1 angiopoietin 1
ATP6V0C ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c
ATP6V0E1 ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1
AZGP1 alpha-2-glycoprotein 1, zinc-binding
BANK1 B-cell scaffold protein with ankyrin repeats 1
BASP1 brain abundant, membrane attached signal protein 1
BAX BCL2-associated X protein
BPI bactericidal/permeability-increasing protein
BTG1 B-cell translocation gene 1, anti-proliferative
CCNG2 cyclin G2
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
CLC Charcot-Leyden crystal galectin
CLIC3 chloride intracellular channel 3
CST7 cystatin F (leukocystatin)
CTSG cathepsin G
CX3CR1 chemokine (C-X3-C motif) receptor 1
CYB5A cytochrome b5 type A (microsomal)
DUSP6 dual specificity phosphatase 6
FCN1 ficolin (collagen/fibrinogen domain containing) 1
FGFR4 fibroblast growth factor receptor 4
GATA2 GATA binding protein 2
GJA1 gap junction protein, alpha 1, 43kDa
GSTP1 glutathione S-transferase pi 1
HBB hemoglobin, beta
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
IFI30 interferon, gamma-inducible protein 30
IGHM immunoglobulin heavy constant mu
IGL immunoglobulin lambda locus
JCHAIN joining chain of multimeric IgA and IgM
KLF2 Kruppel-like factor 2
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
LY75 lymphocyte antigen 75
LYPLA1 lysophospholipase I
MEGF9 multiple EGF-like-domains 9
MKNK2 MAP kinase interacting serine/threonine kinase 2
MNDA myeloid cell nuclear differentiation antigen
MS4A3 membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific)
PLA2G16 phospholipase A2, group XVI
PPL periplakin
PTGDS prostaglandin D2 synthase 21kDa (brain)
RAD23B RAD23 homolog B (S. cerevisiae)
RNF167 ring finger protein 167
S100A12 S100 calcium binding protein A12
S100A8 S100 calcium binding protein A8
S100A9 S100 calcium binding protein A9
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SLPI secretory leukocyte peptidase inhibitor
SNRNP25 small nuclear ribonucleoprotein 25kDa (U11/U12)
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TOB2 transducer of ERBB2, 2
TSPAN13 tetraspanin 13
TUBA4A tubulin, alpha 4a