BRD-K00615600_Unable to generate chemical name O-4537-1_A549_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

77 genes differentially expressed following the BRD-K00615600_Unable to generate chemical name O-4537-1_A549_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
ABHD6 abhydrolase domain containing 6
ADO 2-aminoethanethiol (cysteamine) dioxygenase
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
DKK1 dickkopf WNT signaling pathway inhibitor 1
DSP desmoplakin
FBXL12 F-box and leucine-rich repeat protein 12
FGFR3 fibroblast growth factor receptor 3
GSTM3 glutathione S-transferase mu 3 (brain)
H2BFS H2B histone family, member S (pseudogene)
HIST1H1C histone cluster 1, H1c
HIST1H2BK histone cluster 1, H2bk
IGHM immunoglobulin heavy constant mu
IGKV1-5 immunoglobulin kappa variable 1-5
IGKV4-1 immunoglobulin kappa variable 4-1
KRT19 keratin 19, type I
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2
NCK1 NCK adaptor protein 1
PFKL phosphofructokinase, liver
PGC progastricsin (pepsinogen C)
PTPRO protein tyrosine phosphatase, receptor type, O
RAMP1 receptor (G protein-coupled) activity modifying protein 1
RBP1 retinol binding protein 1, cellular
RELN reelin
RGCC regulator of cell cycle
RPP38 ribonuclease P/MRP 38kDa subunit
SESN1 sestrin 1
SOX9 SRY (sex determining region Y)-box 9
TACSTD2 tumor-associated calcium signal transducer 2
TERT telomerase reverse transcriptase
TPD52L1 tumor protein D52-like 1
ZMAT3 zinc finger, matrin-type 3

decreased expression

Symbol Name
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3
ADCY1 adenylate cyclase 1 (brain)
AIM1 absent in melanoma 1
AQP3 aquaporin 3 (Gill blood group)
ATF5 activating transcription factor 5
C8ORF4 chromosome 8 open reading frame 4
CD24 CD24 molecule
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CDH2 cadherin 2, type 1, N-cadherin (neuronal)
CFLAR CASP8 and FADD-like apoptosis regulator
COL5A2 collagen, type V, alpha 2
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DDIT4 DNA-damage-inducible transcript 4
DENND1B DENN/MADD domain containing 1B
DPP4 dipeptidyl-peptidase 4
DPYSL2 dihydropyrimidinase-like 2
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
EGFR epidermal growth factor receptor
GNAS GNAS complex locus
GPRC5A G protein-coupled receptor, class C, group 5, member A
IGF1R insulin-like growth factor 1 receptor
IGFBP4 insulin-like growth factor binding protein 4
MDFIC MyoD family inhibitor domain containing
MEIS2 Meis homeobox 2
NAMPT nicotinamide phosphoribosyltransferase
NOTCH2 notch 2
NR2F1 nuclear receptor subfamily 2, group F, member 1
NRN1 neuritin 1
NRP1 neuropilin 1
PON2 paraoxonase 2
PON3 paraoxonase 3
RND3 Rho family GTPase 3
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SETBP1 SET binding protein 1
SLC12A2 solute carrier family 12 (sodium/potassium/chloride transporter), member 2
SYBU syntabulin (syntaxin-interacting)
TCF4 transcription factor 4
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TFRC transferrin receptor
TNC tenascin C
TRAF5 TNF receptor-associated factor 5
UGDH UDP-glucose 6-dehydrogenase