BRD-K00615600_Unable to generate chemical name O-4537-1_A375_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

83 genes differentially expressed following the BRD-K00615600_Unable to generate chemical name O-4537-1_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AKAP8L A kinase (PRKA) anchor protein 8-like
ANKRD10 ankyrin repeat domain 10
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CFB complement factor B
CPB1 carboxypeptidase B1 (tissue)
DDB2 damage-specific DNA binding protein 2, 48kDa
FADS1 fatty acid desaturase 1
FAS Fas cell surface death receptor
GFOD1 glucose-fructose oxidoreductase domain containing 1
IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial
KIAA0753 KIAA0753
LOC100505650 uncharacterized LOC100505650
MAGEA3 melanoma antigen family A3
NGRN neugrin, neurite outgrowth associated
OXCT1 3-oxoacid CoA transferase 1
PCDH17 protocadherin 17
PPIF peptidylprolyl isomerase F
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta
PRKCQ protein kinase C, theta
RAMP1 receptor (G protein-coupled) activity modifying protein 1
RBP1 retinol binding protein 1, cellular
SCGB2A1 secretoglobin, family 2A, member 1
SEPP1 selenoprotein P, plasma, 1
SFRP4 secreted frizzled-related protein 4
SLC38A1 solute carrier family 38, member 1
SPON1 spondin 1, extracellular matrix protein
TMOD1 tropomodulin 1
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b
VCAM1 vascular cell adhesion molecule 1
ZNF451 zinc finger protein 451

decreased expression

Symbol Name
ADM adrenomedullin
AK1 adenylate kinase 1
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
ATF5 activating transcription factor 5
BLNK B-cell linker
C9ORF3 chromosome 9 open reading frame 3
CAMK2N1 calcium/calmodulin-dependent protein kinase II inhibitor 1
CAV2 caveolin 2
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CEMIP cell migration inducing protein, hyaluronan binding
CENPE centromere protein E, 312kDa
CTGF connective tissue growth factor
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
CYP4F3 cytochrome P450, family 4, subfamily F, polypeptide 3
DCN decorin
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
ETV1 ets variant 1
EZR ezrin
F3 coagulation factor III (thromboplastin, tissue factor)
GALNT12 polypeptide N-acetylgalactosaminyltransferase 12
GNAQ guanine nucleotide binding protein (G protein), q polypeptide
GNAS GNAS complex locus
GPI glucose-6-phosphate isomerase
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
ITGA6 integrin, alpha 6
KLF4 Kruppel-like factor 4 (gut)
LGR4 leucine-rich repeat containing G protein-coupled receptor 4
MEGF9 multiple EGF-like-domains 9
MNDA myeloid cell nuclear differentiation antigen
MYO6 myosin VI
NCAPD2 non-SMC condensin I complex, subunit D2
PBX1 pre-B-cell leukemia homeobox 1
PCOLCE2 procollagen C-endopeptidase enhancer 2
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
PLS3 plastin 3
PPAP2B phosphatidic acid phosphatase type 2B
PSRC1 proline/serine-rich coiled-coil 1
RAB8A RAB8A, member RAS oncogene family
S100P S100 calcium binding protein P
SELENBP1 selenium binding protein 1
SH3BP4 SH3-domain binding protein 4
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3
SPTBN1 spectrin, beta, non-erythrocytic 1
TMEM123 transmembrane protein 123
TMPRSS2 transmembrane protease, serine 2
TOP2A topoisomerase (DNA) II alpha 170kDa
TUBB4B tubulin, beta 4B class IVb
TUBB6 tubulin, beta 6 class V
UGDH UDP-glucose 6-dehydrogenase
WNK1 WNK lysine deficient protein kinase 1
ZIC1 Zic family member 1