BRD-K00486725_-666_A375_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

25 genes differentially expressed following the BRD-K00486725_-666_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ASNS asparagine synthetase (glutamine-hydrolyzing)
CREB3L2 cAMP responsive element binding protein 3-like 2
DACH1 dachshund family transcription factor 1
FBN2 fibrillin 2
FKBP11 FK506 binding protein 11, 19 kDa
GLRX glutaredoxin (thioltransferase)
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HYOU1 hypoxia up-regulated 1
IGHM immunoglobulin heavy constant mu
IGKC immunoglobulin kappa constant
IGKV1-5 immunoglobulin kappa variable 1-5
IGKV4-1 immunoglobulin kappa variable 4-1
NUCB2 nucleobindin 2
PDIA4 protein disulfide isomerase family A, member 4
RABAC1 Rab acceptor 1 (prenylated)
SDF2L1 stromal cell-derived factor 2-like 1
SEC24D SEC24 family member D
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SPINK4 serine peptidase inhibitor, Kazal type 4
TES testin LIM domain protein
XBP1 X-box binding protein 1

decreased expression

Symbol Name
ENC1 ectodermal-neural cortex 1 (with BTB domain)
MMP7 matrix metallopeptidase 7
SPARC secreted protein, acidic, cysteine-rich (osteonectin)