BRD-K00317371_-666_SW620_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

85 genes differentially expressed following the BRD-K00317371_-666_SW620_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ALDH5A1 aldehyde dehydrogenase 5 family, member A1
ANXA4 annexin A4
ASNS asparagine synthetase (glutamine-hydrolyzing)
BTG1 B-cell translocation gene 1, anti-proliferative
C14ORF132 chromosome 14 open reading frame 132
C6ORF62 chromosome 6 open reading frame 62
CA2 carbonic anhydrase II
CAV1 caveolin 1, caveolae protein, 22kDa
CBS cystathionine-beta-synthase
CBX1 chromobox homolog 1
CD14 CD14 molecule
CD24 CD24 molecule
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CHN1 chimerin 1
CLC Charcot-Leyden crystal galectin
CPA3 carboxypeptidase A3 (mast cell)
CSTA cystatin A (stefin A)
CXCL9 chemokine (C-X-C motif) ligand 9
DDIT4 DNA-damage-inducible transcript 4
DDX21 DEAD (Asp-Glu-Ala-Asp) box helicase 21
DEPTOR DEP domain containing MTOR-interacting protein
G3BP1 GTPase activating protein (SH3 domain) binding protein 1
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HMOX1 heme oxygenase 1
JCHAIN joining chain of multimeric IgA and IgM
KRT14 keratin 14, type I
LUM lumican
MKNK1 MAP kinase interacting serine/threonine kinase 1
MPO myeloperoxidase
MTSS1 metastasis suppressor 1
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1
NARFL nuclear prelamin A recognition factor-like
ORC1 origin recognition complex, subunit 1
PFN2 profilin 2
PRR15L proline rich 15-like
RSRP1 arginine/serine-rich protein 1
S100A8 S100 calcium binding protein A8
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
SLC38A1 solute carrier family 38, member 1
SLC38A2 solute carrier family 38, member 2
SNX13 sorting nexin 13
SPINK1 serine peptidase inhibitor, Kazal type 1
TFRC transferrin receptor
TRIB1 tribbles pseudokinase 1
TRIB3 tribbles pseudokinase 3
TRIM2 tripartite motif containing 2
TSEN2 TSEN2 tRNA splicing endonuclease subunit

decreased expression

Symbol Name
ANK2 ankyrin 2, neuronal
CCNI cyclin I
CCP110 centriolar coiled coil protein 110kDa
CD36 CD36 molecule (thrombospondin receptor)
COLEC12 collectin sub-family member 12
CXCL14 chemokine (C-X-C motif) ligand 14
DACH1 dachshund family transcription factor 1
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
DLC1 DLC1 Rho GTPase activating protein
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1
FABP4 fatty acid binding protein 4, adipocyte
FAM134B family with sequence similarity 134, member B
FOLR1 folate receptor 1 (adult)
GALNT11 polypeptide N-acetylgalactosaminyltransferase 11
GPX3 glutathione peroxidase 3
KAZN kazrin, periplakin interacting protein
KDM5D lysine (K)-specific demethylase 5D
LAMP1 lysosomal-associated membrane protein 1
LPL lipoprotein lipase
LRRC16A leucine rich repeat containing 16A
MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog
MGP matrix Gla protein
MYL6B myosin, light chain 6B, alkali, smooth muscle and non-muscle
NPY neuropeptide Y
NUP98 nucleoporin 98kDa
PDIA3 protein disulfide isomerase family A, member 3
PECAM1 platelet/endothelial cell adhesion molecule 1
PGC progastricsin (pepsinogen C)
PLIN2 perilipin 2
RGS5 regulator of G-protein signaling 5
SAT1 spermidine/spermine N1-acetyltransferase 1
SPINT2 serine peptidase inhibitor, Kunitz type, 2
SRP72 signal recognition particle 72kDa
SRPX sushi-repeat containing protein, X-linked
TBC1D4 TBC1 domain family, member 4
VWF von Willebrand factor