BRD-K00007652_-666_PC3_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

35 genes differentially expressed following the BRD-K00007652_-666_PC3_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AGR2 anterior gradient 2
AHNAK2 AHNAK nucleoprotein 2
AQP3 aquaporin 3 (Gill blood group)
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CFD complement factor D (adipsin)
CHRDL1 chordin-like 1
DAPK1 death-associated protein kinase 1
DDIT4 DNA-damage-inducible transcript 4
FADS1 fatty acid desaturase 1
FGFR3 fibroblast growth factor receptor 3
HMOX1 heme oxygenase 1
INSIG1 insulin induced gene 1
LDLR low density lipoprotein receptor
LMO3 LIM domain only 3 (rhombotin-like 2)
MGP matrix Gla protein
OPN3 opsin 3
RHOB ras homolog family member B
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SQLE squalene epoxidase
STK26 serine/threonine protein kinase 26

decreased expression

Symbol Name
ADAMTS5 ADAM metallopeptidase with thrombospondin type 1 motif, 5
CA2 carbonic anhydrase II
CPE carboxypeptidase E
CXCL9 chemokine (C-X-C motif) ligand 9
DHRS2 dehydrogenase/reductase (SDR family) member 2
DST dystonin
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
HOXA10 homeobox A10
MMP9 matrix metallopeptidase 9
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
PDZK1 PDZ domain containing 1
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
TOMM70A translocase of outer mitochondrial membrane 70 homolog A (S. cerevisiae)