BRD-A98444709_-666_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

99 genes differentially expressed following the BRD-A98444709_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ASMTL acetylserotonin O-methyltransferase-like
ATP6V1D ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D
CA2 carbonic anhydrase II
CALD1 caldesmon 1
CCND2 cyclin D2
CD40 CD40 molecule, TNF receptor superfamily member 5
CD44 CD44 molecule (Indian blood group)
CEACAM7 carcinoembryonic antigen-related cell adhesion molecule 7
CLCA1 chloride channel accessory 1
CLIC5 chloride intracellular channel 5
CXADR coxsackie virus and adenovirus receptor
CXCL11 chemokine (C-X-C motif) ligand 11
DDX17 DEAD (Asp-Glu-Ala-Asp) box helicase 17
EFNB2 ephrin-B2
EIF5A eukaryotic translation initiation factor 5A
EPHX2 epoxide hydrolase 2, cytoplasmic
FGFR2 fibroblast growth factor receptor 2
GRB10 growth factor receptor-bound protein 10
GREM1 gremlin 1, DAN family BMP antagonist
H2BFS H2B histone family, member S (pseudogene)
HIC2 hypermethylated in cancer 2
HIST1H1C histone cluster 1, H1c
HIST1H2BD histone cluster 1, H2bd
HIST1H2BK histone cluster 1, H2bk
HIST2H2BE histone cluster 2, H2be
IDO1 indoleamine 2,3-dioxygenase 1
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
ITM2C integral membrane protein 2C
JAG1 jagged 1
KCNJ2 potassium channel, inwardly rectifying subfamily J, member 2
MAN2A1 mannosidase, alpha, class 2A, member 1
METRN meteorin, glial cell differentiation regulator
MMP12 matrix metallopeptidase 12
MS4A12 membrane-spanning 4-domains, subfamily A, member 12
NCAM1 neural cell adhesion molecule 1
NOX1 NADPH oxidase 1
NR4A2 nuclear receptor subfamily 4, group A, member 2
PDE9A phosphodiesterase 9A
PFKL phosphofructokinase, liver
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid)
PSPH phosphoserine phosphatase
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1
SIK1 salt-inducible kinase 1
SLC26A2 solute carrier family 26 (anion exchanger), member 2
SLC26A3 solute carrier family 26 (anion exchanger), member 3
SLC30A1 solute carrier family 30 (zinc transporter), member 1
SRGN serglycin
ST6GALNAC5 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5
TCTA T-cell leukemia translocation altered
TMSB15A thymosin beta 15a
TRIM36 tripartite motif containing 36
UGT2B17 UDP glucuronosyltransferase 2 family, polypeptide B17
VEGFA vascular endothelial growth factor A

decreased expression

Symbol Name
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
AKR1C3 aldo-keto reductase family 1, member C3
ANK3 ankyrin 3, node of Ranvier (ankyrin G)
APOD apolipoprotein D
AQP3 aquaporin 3 (Gill blood group)
CLPX caseinolytic mitochondrial matrix peptidase chaperone subunit
COCH cochlin
CRISP3 cysteine-rich secretory protein 3
CTSH cathepsin H
CXCL14 chemokine (C-X-C motif) ligand 14
DCN decorin
DDAH1 dimethylarginine dimethylaminohydrolase 1
DENND2D DENN/MADD domain containing 2D
DKK1 dickkopf WNT signaling pathway inhibitor 1
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
FAM57A family with sequence similarity 57, member A
GALNT6 polypeptide N-acetylgalactosaminyltransferase 6
GRB14 growth factor receptor-bound protein 14
GRWD1 glutamate-rich WD repeat containing 1
HOXC6 homeobox C6
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
KIF14 kinesin family member 14
KYNU kynureninase
LSM14A LSM14A, SCD6 homolog A (S. cerevisiae)
LTF lactotransferrin
MAPK13 mitogen-activated protein kinase 13
MGP matrix Gla protein
MMP7 matrix metallopeptidase 7
NQO2 NAD(P)H dehydrogenase, quinone 2
PIGB phosphatidylinositol glycan anchor biosynthesis, class B
PLA2G16 phospholipase A2, group XVI
S100A11 S100 calcium binding protein A11
SDC1 syndecan 1
SERPINB1 serpin peptidase inhibitor, clade B (ovalbumin), member 1
SPDEF SAM pointed domain containing ETS transcription factor
SPINK1 serine peptidase inhibitor, Kazal type 1
STC2 stanniocalcin 2
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TGFB3 transforming growth factor, beta 3
TPBG trophoblast glycoprotein
VCAN versican
ZIC1 Zic family member 1
ZNF512B zinc finger protein 512B