BRD-A98378129_-666_HT29_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

30 genes differentially expressed following the BRD-A98378129_-666_HT29_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
ANK3 ankyrin 3, node of Ranvier (ankyrin G)
ARPP19 cAMP-regulated phosphoprotein, 19kDa
BAX BCL2-associated X protein
DDIT4 DNA-damage-inducible transcript 4
GCLC glutamate-cysteine ligase, catalytic subunit
GCLM glutamate-cysteine ligase, modifier subunit
HMOX1 heme oxygenase 1
KIF14 kinesin family member 14
MET MET proto-oncogene, receptor tyrosine kinase
NAMPT nicotinamide phosphoribosyltransferase
NQO1 NAD(P)H dehydrogenase, quinone 1
PRDX4 peroxiredoxin 4
RAD23B RAD23 homolog B (S. cerevisiae)
SFRP4 secreted frizzled-related protein 4
SLC39A14 solute carrier family 39 (zinc transporter), member 14
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b

decreased expression

Symbol Name
BPHL biphenyl hydrolase-like (serine hydrolase)
COL6A1 collagen, type VI, alpha 1
COL6A2 collagen, type VI, alpha 2
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1
DACH1 dachshund family transcription factor 1
DHRS2 dehydrogenase/reductase (SDR family) member 2
DLK1 delta-like 1 homolog (Drosophila)
FOS FBJ murine osteosarcoma viral oncogene homolog
IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial
MCOLN1 mucolipin 1
NPTX2 neuronal pentraxin II