BRD-A98378129_-666_HEPG2_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

58 genes differentially expressed following the BRD-A98378129_-666_HEPG2_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
BASP1 brain abundant, membrane attached signal protein 1
BDH2 3-hydroxybutyrate dehydrogenase, type 2
BST2 bone marrow stromal cell antigen 2
C2CD2 C2 calcium-dependent domain containing 2
CLU clusterin
CXCL13 chemokine (C-X-C motif) ligand 13
DDIT4 DNA-damage-inducible transcript 4
HMOX1 heme oxygenase 1
HSPB8 heat shock 22kDa protein 8
IGHM immunoglobulin heavy constant mu
IGKC immunoglobulin kappa constant
IGKV1-5 immunoglobulin kappa variable 1-5
IGKV4-1 immunoglobulin kappa variable 4-1
IGLV3-19 immunoglobulin lambda variable 3-19
IKZF1 IKAROS family zinc finger 1 (Ikaros)
PLA2G16 phospholipase A2, group XVI
PLAC8 placenta-specific 8
RCN1 reticulocalbin 1, EF-hand calcium binding domain
SELL selectin L
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
UGDH UDP-glucose 6-dehydrogenase

decreased expression

Symbol Name
ACTA2 actin, alpha 2, smooth muscle, aorta
ARHGDIA Rho GDP dissociation inhibitor (GDI) alpha
ASPN asporin
CCL20 chemokine (C-C motif) ligand 20
CD24 CD24 molecule
CD44 CD44 molecule (Indian blood group)
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)
COL1A1 collagen, type I, alpha 1
COL6A1 collagen, type VI, alpha 1
FAM198B family with sequence similarity 198, member B
FGFR1 fibroblast growth factor receptor 1
FN1 fibronectin 1
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
JAG1 jagged 1
LEF1 lymphoid enhancer-binding factor 1
LOC100505650 uncharacterized LOC100505650
LPAR6 lysophosphatidic acid receptor 6
LRRC17 leucine rich repeat containing 17
MECOM MDS1 and EVI1 complex locus
MMP14 matrix metallopeptidase 14 (membrane-inserted)
MPZL2 myelin protein zero-like 2
PLP1 proteolipid protein 1
POSTN periostin, osteoblast specific factor
PRAME preferentially expressed antigen in melanoma
PTGER3 prostaglandin E receptor 3 (subtype EP3)
PTGER4 prostaglandin E receptor 4 (subtype EP4)
PTPRO protein tyrosine phosphatase, receptor type, O
RNH1 ribonuclease/angiogenin inhibitor 1
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
SULF1 sulfatase 1
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
THBS1 thrombospondin 1
THBS2 thrombospondin 2
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
VCAN versican