BRD-A96799240_GR-109_MCF7_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

122 genes differentially expressed following the BRD-A96799240_GR-109_MCF7_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
A2M alpha-2-macroglobulin
ADGRG2 adhesion G protein-coupled receptor G2
ALDH1A3 aldehyde dehydrogenase 1 family, member A3
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide
BHLHE41 basic helix-loop-helix family, member e41
CAMK2N1 calcium/calmodulin-dependent protein kinase II inhibitor 1
CPE carboxypeptidase E
CXCL13 chemokine (C-X-C motif) ligand 13
DDIT4 DNA-damage-inducible transcript 4
DHRS3 dehydrogenase/reductase (SDR family) member 3
EFNB2 ephrin-B2
EGFL6 EGF-like-domain, multiple 6
EPAS1 endothelial PAS domain protein 1
EPB41L3 erythrocyte membrane protein band 4.1-like 3
FUT1 fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group)
GNAS GNAS complex locus
HOXA5 homeobox A5
IGFBP3 insulin-like growth factor binding protein 3
IGHM immunoglobulin heavy constant mu
IGKC immunoglobulin kappa constant
IGKV1-5 immunoglobulin kappa variable 1-5
IGL immunoglobulin lambda locus
KCTD12 potassium channel tetramerization domain containing 12
KDR kinase insert domain receptor
KRT13 keratin 13, type I
LAMA3 laminin, alpha 3
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
LYPD1 LY6/PLAUR domain containing 1
MAGEA3 melanoma antigen family A3
MGP matrix Gla protein
MLEC malectin
MME membrane metallo-endopeptidase
NDRG1 N-myc downstream regulated 1
NID1 nidogen 1
NPTX2 neuronal pentraxin II
NR2F1 nuclear receptor subfamily 2, group F, member 1
PCP4 Purkinje cell protein 4
PEG10 paternally expressed 10
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
POU2AF1 POU class 2 associating factor 1
PRKCD protein kinase C, delta
PRSS23 protease, serine, 23
RGCC regulator of cell cycle
RGS5 regulator of G-protein signaling 5
SERPING1 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1
SKAP2 src kinase associated phosphoprotein 2
SNAI2 snail family zinc finger 2
SORL1 sortilin-related receptor, L(DLR class) A repeats containing
SPARCL1 SPARC-like 1 (hevin)
SQSTM1 sequestosome 1
STON1 stonin 1
TNS1 tensin 1
TRIB1 tribbles pseudokinase 1
TSC22D3 TSC22 domain family, member 3
VWF von Willebrand factor
WASF1 WAS protein family, member 1
XIST X inactive specific transcript (non-protein coding)
ZBED2 zinc finger, BED-type containing 2

decreased expression

Symbol Name
ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide
ALCAM activated leukocyte cell adhesion molecule
ALDH3B2 aldehyde dehydrogenase 3 family, member B2
ANXA5 annexin A5
ARMT1 acidic residue methyltransferase 1
ASAH1 N-acylsphingosine amidohydrolase (acid ceramidase) 1
ASRGL1 asparaginase like 1
ATP6V1G1 ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G1
CA12 carbonic anhydrase XII
CDC25B cell division cycle 25B
CLIC4 chloride intracellular channel 4
CORO1C coronin, actin binding protein, 1C
CRIP2 cysteine-rich protein 2
DKK1 dickkopf WNT signaling pathway inhibitor 1
DPYSL2 dihydropyrimidinase-like 2
EIF4B eukaryotic translation initiation factor 4B
EIF5A eukaryotic translation initiation factor 5A
EMP3 epithelial membrane protein 3
ESR1 estrogen receptor 1
EVL Enah/Vasp-like
GALNT6 polypeptide N-acetylgalactosaminyltransferase 6
GATA3 GATA binding protein 3
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
IFI44L interferon-induced protein 44-like
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IFITM1 interferon induced transmembrane protein 1
IFITM2 interferon induced transmembrane protein 2
IRX5 iroquois homeobox 5
LAGE3 L antigen family, member 3
LTF lactotransferrin
LYPLA1 lysophospholipase I
MANSC1 MANSC domain containing 1
MUC1 mucin 1, cell surface associated
MUC5B mucin 5B, oligomeric mucus/gel-forming
NAT1 N-acetyltransferase 1 (arylamine N-acetyltransferase)
NPY neuropeptide Y
PDZK1 PDZ domain containing 1
PGAM1 phosphoglycerate mutase 1 (brain)
PKM pyruvate kinase, muscle
PLEKHF2 pleckstrin homology domain containing, family F (with FYVE domain) member 2
PTP4A2 protein tyrosine phosphatase type IVA, member 2
RPL37A ribosomal protein L37a
RPL38 ribosomal protein L38
RPS11 ribosomal protein S11
RTN3 reticulon 3
SCGB1D2 secretoglobin, family 1D, member 2
SCGB2A1 secretoglobin, family 2A, member 1
SCGB2A2 secretoglobin, family 2A, member 2
SEC22B SEC22 vesicle trafficking protein homolog B (S. cerevisiae) (gene/pseudogene)
SLC26A2 solute carrier family 26 (anion exchanger), member 2
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4
SPDEF SAM pointed domain containing ETS transcription factor
TFF1 trefoil factor 1
TFF3 trefoil factor 3 (intestinal)
TOX3 TOX high mobility group box family member 3
TSPAN4 tetraspanin 4
TSPAN8 tetraspanin 8
UGCG UDP-glucose ceramide glucosyltransferase
VAMP7 vesicle-associated membrane protein 7
VAT1 vesicle amine transport 1
VBP1 von Hippel-Lindau binding protein 1
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon