BRD-A95820578_NP-006304_VCAP_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

118 genes differentially expressed following the BRD-A95820578_NP-006304_VCAP_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADRB2 adrenoceptor beta 2, surface
AKAP7 A kinase (PRKA) anchor protein 7
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase)
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
ALCAM activated leukocyte cell adhesion molecule
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
ALDH1A3 aldehyde dehydrogenase 1 family, member A3
AMD1 adenosylmethionine decarboxylase 1
ANXA5 annexin A5
AQP3 aquaporin 3 (Gill blood group)
ATP6V1D ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D
BIK BCL2-interacting killer (apoptosis-inducing)
BLVRB biliverdin reductase B
C6ORF48 chromosome 6 open reading frame 48
CALD1 caldesmon 1
CLK4 CDC-like kinase 4
CST3 cystatin C
CSTA cystatin A (stefin A)
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
ECI2 enoyl-CoA delta isomerase 2
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
FGF13 fibroblast growth factor 13
FLNB filamin B, beta
FUCA1 fucosidase, alpha-L- 1, tissue
FXYD3 FXYD domain containing ion transport regulator 3
GALNT12 polypeptide N-acetylgalactosaminyltransferase 12
IFI6 interferon, alpha-inducible protein 6
KLF4 Kruppel-like factor 4 (gut)
LAMA3 laminin, alpha 3
LEPR leptin receptor
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae)
LTBP3 latent transforming growth factor beta binding protein 3
LUC7L3 LUC7-like 3 (S. cerevisiae)
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MARCH8 membrane-associated ring finger (C3HC4) 8, E3 ubiquitin protein ligase
MARCKSL1 MARCKS-like 1
MICALL1 MICAL-like 1
MKRN1 makorin ring finger protein 1
NKX3-1 NK3 homeobox 1
NPC2 Niemann-Pick disease, type C2
NQO1 NAD(P)H dehydrogenase, quinone 1
OAT ornithine aminotransferase
PDLIM5 PDZ and LIM domain 5
PEX11A peroxisomal biogenesis factor 11 alpha
RAMP1 receptor (G protein-coupled) activity modifying protein 1
RARRES1 retinoic acid receptor responder (tazarotene induced) 1
SLC15A2 solute carrier family 15 (oligopeptide transporter), member 2
SLC19A2 solute carrier family 19 (thiamine transporter), member 2
SLC22A5 solute carrier family 22 (organic cation/carnitine transporter), member 5
SLC44A4 solute carrier family 44, member 4
SORD sorbitol dehydrogenase
SOX9 SRY (sex determining region Y)-box 9
SRSF6 serine/arginine-rich splicing factor 6
SRSF7 serine/arginine-rich splicing factor 7
STEAP1 six transmembrane epithelial antigen of the prostate 1
TGFBI transforming growth factor, beta-induced, 68kDa
TMED3 transmembrane emp24 protein transport domain containing 3
TMEM251 transmembrane protein 251
TRAPPC3 trafficking protein particle complex 3
TRIB2 tribbles pseudokinase 2
TSPAN4 tetraspanin 4
WWP1 WW domain containing E3 ubiquitin protein ligase 1

decreased expression

Symbol Name
ABCA8 ATP-binding cassette, sub-family A (ABC1), member 8
ACTR2 ARP2 actin-related protein 2 homolog (yeast)
ADGRF5 adhesion G protein-coupled receptor F5
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
AMIGO2 adhesion molecule with Ig-like domain 2
ANOS1 anosmin 1
ARL4C ADP-ribosylation factor-like 4C
ARMCX1 armadillo repeat containing, X-linked 1
ARMCX2 armadillo repeat containing, X-linked 2
AUTS2 autism susceptibility candidate 2
CCNE2 cyclin E2
COPA coatomer protein complex, subunit alpha
CX3CR1 chemokine (C-X3-C motif) receptor 1
CXCR4 chemokine (C-X-C motif) receptor 4
DEPTOR DEP domain containing MTOR-interacting protein
DFFA DNA fragmentation factor, 45kDa, alpha polypeptide
DHX9 DEAH (Asp-Glu-Ala-His) box helicase 9
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
ENC1 ectodermal-neural cortex 1 (with BTB domain)
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1
GPM6B glycoprotein M6B
GPR37 G protein-coupled receptor 37 (endothelin receptor type B-like)
HEY1 hes-related family bHLH transcription factor with YRPW motif 1
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HOXD1 homeobox D1
INSM1 insulinoma-associated 1
KIF1A kinesin family member 1A
LAMP5 lysosomal-associated membrane protein family, member 5
LGALS8 lectin, galactoside-binding, soluble, 8
LMO3 LIM domain only 3 (rhombotin-like 2)
LRRN3 leucine rich repeat neuronal 3
MDFIC MyoD family inhibitor domain containing
MREG melanoregulin
NCAM1 neural cell adhesion molecule 1
NRCAM neuronal cell adhesion molecule
OSBPL1A oxysterol binding protein-like 1A
PSRC1 proline/serine-rich coiled-coil 1
RAD21 RAD21 homolog (S. pombe)
RBP4 retinol binding protein 4, plasma
RCBTB2 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
RGS5 regulator of G-protein signaling 5
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila)
RUNX1T1 runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
SCG5 secretogranin V
SEPT2 septin 2
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SGCE sarcoglycan, epsilon
SORL1 sortilin-related receptor, L(DLR class) A repeats containing
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila)
SST somatostatin
TIMP2 TIMP metallopeptidase inhibitor 2
TTN titin
WFDC1 WAP four-disulfide core domain 1
XIST X inactive specific transcript (non-protein coding)