BRD-A94413429_-666_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

84 genes differentially expressed following the BRD-A94413429_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACLY ATP citrate lyase
ACSL3 acyl-CoA synthetase long-chain family member 3
AK4 adenylate kinase 4
AZGP1 alpha-2-glycoprotein 1, zinc-binding
BHLHE40 basic helix-loop-helix family, member e40
CD24 CD24 molecule
CD44 CD44 molecule (Indian blood group)
CYP51A1 cytochrome P450, family 51, subfamily A, polypeptide 1
DDIT4 DNA-damage-inducible transcript 4
DHCR24 24-dehydrocholesterol reductase
DHCR7 7-dehydrocholesterol reductase
DUSP4 dual specificity phosphatase 4
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
EBP emopamil binding protein (sterol isomerase)
ELOVL6 ELOVL fatty acid elongase 6
FADS1 fatty acid desaturase 1
FADS2 fatty acid desaturase 2
FASN fatty acid synthase
FDFT1 farnesyl-diphosphate farnesyltransferase 1
FDPS farnesyl diphosphate synthase
FOXO3 forkhead box O3
G6PD glucose-6-phosphate dehydrogenase
HBP1 HMG-box transcription factor 1
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
HMOX1 heme oxygenase 1
HSD17B7 hydroxysteroid (17-beta) dehydrogenase 7
IDI1 isopentenyl-diphosphate delta isomerase 1
INSIG1 insulin induced gene 1
LDLR low density lipoprotein receptor
LPIN1 lipin 1
LSS lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
MSMO1 methylsterol monooxygenase 1
PBX3 pre-B-cell leukemia homeobox 3
PSD3 pleckstrin and Sec7 domain containing 3
PTGER3 prostaglandin E receptor 3 (subtype EP3)
S100A2 S100 calcium binding protein A2
SC5D sterol-C5-desaturase
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SLCO4A1 solute carrier organic anion transporter family, member 4A1
SQLE squalene epoxidase
SREBF1 sterol regulatory element binding transcription factor 1
SYT1 synaptotagmin I
TAC1 tachykinin, precursor 1
TBC1D9 TBC1 domain family, member 9 (with GRAM domain)
TMEM97 transmembrane protein 97
TNC tenascin C
TNFAIP6 tumor necrosis factor, alpha-induced protein 6
TNNT1 troponin T type 1 (skeletal, slow)
ZBTB18 zinc finger and BTB domain containing 18
ZNF217 zinc finger protein 217

decreased expression

Symbol Name
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide
AKAP12 A kinase (PRKA) anchor protein 12
CADM1 cell adhesion molecule 1
CCNE2 cyclin E2
CCT2 chaperonin containing TCP1, subunit 2 (beta)
CHMP4A charged multivesicular body protein 4A
CMAHP cytidine monophospho-N-acetylneuraminic acid hydroxylase, pseudogene
CSTA cystatin A (stefin A)
EXOSC4 exosome component 4
GPRC5A G protein-coupled receptor, class C, group 5, member A
HIST1H2AC histone cluster 1, H2ac
HIST1H2BK histone cluster 1, H2bk
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HTRA1 HtrA serine peptidase 1
IGHM immunoglobulin heavy constant mu
IGKC immunoglobulin kappa constant
IGL immunoglobulin lambda locus
KRT7 keratin 7, type II
LGALS3 lectin, galactoside-binding, soluble, 3
MCOLN1 mucolipin 1
MRPS2 mitochondrial ribosomal protein S2
MUC4 mucin 4, cell surface associated
NOP16 NOP16 nucleolar protein
PTGDS prostaglandin D2 synthase 21kDa (brain)
RARRES1 retinoic acid receptor responder (tazarotene induced) 1
RRP12 ribosomal RNA processing 12 homolog (S. cerevisiae)
S100P S100 calcium binding protein P
STAT1 signal transducer and activator of transcription 1, 91kDa
UTP14A UTP14, U3 small nucleolar ribonucleoprotein, homolog A (yeast)