BRD-A93393712_-666_MCF7_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

47 genes differentially expressed following the BRD-A93393712_-666_MCF7_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADM adrenomedullin
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
AKR1C1 aldo-keto reductase family 1, member C1
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial)
ALDH3A2 aldehyde dehydrogenase 3 family, member A2
AMFR autocrine motility factor receptor, E3 ubiquitin protein ligase
CKB creatine kinase, brain
CLU clusterin
CTSL cathepsin L
DLK1 delta-like 1 homolog (Drosophila)
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic)
EPN2 epsin 2
GCLM glutamate-cysteine ligase, modifier subunit
HMOX1 heme oxygenase 1
MICALL1 MICAL-like 1
MIR22HG MIR22 host gene
S100A8 S100 calcium binding protein A8
S100A9 S100 calcium binding protein A9
S100P S100 calcium binding protein P
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
TPM2 tropomyosin 2 (beta)
TXNRD1 thioredoxin reductase 1

decreased expression

Symbol Name
AHR aryl hydrocarbon receptor
CCNA2 cyclin A2
CDK1 cyclin-dependent kinase 1
CFB complement factor B
COL1A1 collagen, type I, alpha 1
EIF5A eukaryotic translation initiation factor 5A
ENC1 ectodermal-neural cortex 1 (with BTB domain)
EPS8 epidermal growth factor receptor pathway substrate 8
EVL Enah/Vasp-like
FAP fibroblast activation protein, alpha
FBP1 fructose-1,6-bisphosphatase 1
HOXC6 homeobox C6
HSPA8 heat shock 70kDa protein 8
IGF1 insulin-like growth factor 1 (somatomedin C)
MAPT microtubule-associated protein tau
MMP7 matrix metallopeptidase 7
MUC1 mucin 1, cell surface associated
MYH10 myosin, heavy chain 10, non-muscle
NREP neuronal regeneration related protein
NUAK1 NUAK family, SNF1-like kinase, 1
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit
SYT1 synaptotagmin I
TMC5 transmembrane channel-like 5
UGCG UDP-glucose ceramide glucosyltransferase