BRD-A93393712_-666_HT29_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

95 genes differentially expressed following the BRD-A93393712_-666_HT29_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADM adrenomedullin
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
BAG3 BCL2-associated athanogene 3
CBR3 carbonyl reductase 3
CCR1 chemokine (C-C motif) receptor 1
CD14 CD14 molecule
CD163 CD163 molecule
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CEBPD CCAAT/enhancer binding protein (C/EBP), delta
CLU clusterin
CTSL cathepsin L
DIO2 deiodinase, iodothyronine, type II
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
FCGR1B Fc fragment of IgG, high affinity Ib, receptor (CD64)
FOSL1 FOS-like antigen 1
G0S2 G0/G1 switch 2
G6PD glucose-6-phosphate dehydrogenase
GCLM glutamate-cysteine ligase, modifier subunit
HBB hemoglobin, beta
HK2 hexokinase 2
HMOX1 heme oxygenase 1
HSPA1A heat shock 70kDa protein 1A
HSPA6 heat shock 70kDa protein 6 (HSP70B')
HSPH1 heat shock 105kDa/110kDa protein 1
IMPA2 inositol(myo)-1(or 4)-monophosphatase 2
KRT6A keratin 6A, type II
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
MUC5B mucin 5B, oligomeric mucus/gel-forming
NAMPT nicotinamide phosphoribosyltransferase
NQO1 NAD(P)H dehydrogenase, quinone 1
PCOLCE2 procollagen C-endopeptidase enhancer 2
PGD phosphogluconate dehydrogenase
PHLDA1 pleckstrin homology-like domain, family A, member 1
PLIN2 perilipin 2
RHOB ras homolog family member B
S100A12 S100 calcium binding protein A12
S100A2 S100 calcium binding protein A2
S100P S100 calcium binding protein P
SEH1L SEH1-like (S. cerevisiae)
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SFN stratifin
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SPRR2B small proline-rich protein 2B
SQSTM1 sequestosome 1
TACSTD2 tumor-associated calcium signal transducer 2
TPD52L2 tumor protein D52-like 2
TRBC1 T cell receptor beta constant 1
TRIM16 tripartite motif containing 16
TXNRD1 thioredoxin reductase 1
UGDH UDP-glucose 6-dehydrogenase
UPP1 uridine phosphorylase 1

decreased expression

Symbol Name
A2M alpha-2-macroglobulin
ADD3 adducin 3 (gamma)
APOD apolipoprotein D
AREG amphiregulin
BIK BCL2-interacting killer (apoptosis-inducing)
CD24 CD24 molecule
CDH17 cadherin 17, LI cadherin (liver-intestine)
CLMN calmin (calponin-like, transmembrane)
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
FABP1 fatty acid binding protein 1, liver
FARP1 FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived)
FBLN1 fibulin 1
HOXA5 homeobox A5
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
IGHM immunoglobulin heavy constant mu
JCHAIN joining chain of multimeric IgA and IgM
KIAA0226L KIAA0226-like
KLF5 Kruppel-like factor 5 (intestinal)
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
MARCKS myristoylated alanine-rich protein kinase C substrate
MME membrane metallo-endopeptidase
NRIP1 nuclear receptor interacting protein 1
PAPSS1 3'-phosphoadenosine 5'-phosphosulfate synthase 1
PDCD4 programmed cell death 4 (neoplastic transformation inhibitor)
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
RASGRP3 RAS guanyl releasing protein 3 (calcium and DAG-regulated)
RGS13 regulator of G-protein signaling 13
RGS2 regulator of G-protein signaling 2
SI sucrase-isomaltase (alpha-glucosidase)
SLC26A3 solute carrier family 26 (anion exchanger), member 3
SOX4 SRY (sex determining region Y)-box 4
SPINK1 serine peptidase inhibitor, Kazal type 1
SPON1 spondin 1, extracellular matrix protein
SST somatostatin
TFPI2 tissue factor pathway inhibitor 2
TNS3 tensin 3
TRIM2 tripartite motif containing 2
UGT2B17 UDP glucuronosyltransferase 2 family, polypeptide B17
VTCN1 V-set domain containing T cell activation inhibitor 1