BRD-A92177080_-666_A375_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

79 genes differentially expressed following the BRD-A92177080_-666_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide
C4BPA complement component 4 binding protein, alpha
CADM1 cell adhesion molecule 1
CCL19 chemokine (C-C motif) ligand 19
COL4A2 collagen, type IV, alpha 2
CPM carboxypeptidase M
CTH cystathionine gamma-lyase
CXADR coxsackie virus and adenovirus receptor
DDIT4 DNA-damage-inducible transcript 4
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
FABP4 fatty acid binding protein 4, adipocyte
FOLR1 folate receptor 1 (adult)
FOS FBJ murine osteosarcoma viral oncogene homolog
FOSB FBJ murine osteosarcoma viral oncogene homolog B
IDE insulin-degrading enzyme
IGFBP7 insulin-like growth factor binding protein 7
JADE2 jade family PHD finger 2
KDM5D lysine (K)-specific demethylase 5D
KLF9 Kruppel-like factor 9
KRT7 keratin 7, type II
KYNU kynureninase
LAPTM4B lysosomal protein transmembrane 4 beta
LPL lipoprotein lipase
MAGEA3 melanoma antigen family A3
MAOA monoamine oxidase A
MSN moesin
MT1E metallothionein 1E
MT1F metallothionein 1F
MT1M metallothionein 1M
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NR4A2 nuclear receptor subfamily 4, group A, member 2
PDK4 pyruvate dehydrogenase kinase, isozyme 4
PGC progastricsin (pepsinogen C)
RAMP1 receptor (G protein-coupled) activity modifying protein 1
RPS4Y1 ribosomal protein S4, Y-linked 1
SCNN1A sodium channel, non voltage gated 1 alpha subunit
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans)
SIK1 salt-inducible kinase 1
SNX10 sorting nexin 10
SORBS2 sorbin and SH3 domain containing 2
SORD sorbitol dehydrogenase
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
ZBTB38 zinc finger and BTB domain containing 38

decreased expression

Symbol Name
CA12 carbonic anhydrase XII
CA2 carbonic anhydrase II
CD14 CD14 molecule
CEMIP cell migration inducing protein, hyaluronan binding
CX3CR1 chemokine (C-X3-C motif) receptor 1
FAP fibroblast activation protein, alpha
FCGRT Fc fragment of IgG, receptor, transporter, alpha
FPR1 formyl peptide receptor 1
GALNT6 polypeptide N-acetylgalactosaminyltransferase 6
GUSBP3 glucuronidase, beta pseudogene 3
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
HSPA1A heat shock 70kDa protein 1A
HSPA6 heat shock 70kDa protein 6 (HSP70B')
IER3 immediate early response 3
IER5 immediate early response 5
IFRD1 interferon-related developmental regulator 1
IGFBP3 insulin-like growth factor binding protein 3
IGHD immunoglobulin heavy constant delta
KIAA1033 KIAA1033
KRT14 keratin 14, type I
KRT4 keratin 4, type II
LST1 leukocyte specific transcript 1
MAN1A1 mannosidase, alpha, class 1A, member 1
NDUFA4L2 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2
NOTCH3 notch 3
NSG1 neuron specific gene family member 1
PLK2 polo-like kinase 2
PTN pleiotrophin
S100A8 S100 calcium binding protein A8
S100A9 S100 calcium binding protein A9
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2
SULF1 sulfatase 1
TKT transketolase
XIST X inactive specific transcript (non-protein coding)