BRD-A90643929_-666_SKB_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

112 genes differentially expressed following the BRD-A90643929_-666_SKB_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ALOX5 arachidonate 5-lipoxygenase
ARL4C ADP-ribosylation factor-like 4C
BST2 bone marrow stromal cell antigen 2
BTN3A3 butyrophilin, subfamily 3, member A3
C19ORF66 chromosome 19 open reading frame 66
CCL8 chemokine (C-C motif) ligand 8
CDK17 cyclin-dependent kinase 17
CLDN3 claudin 3
CSRP1 cysteine and glycine-rich protein 1
CXCL10 chemokine (C-X-C motif) ligand 10
CXCL11 chemokine (C-X-C motif) ligand 11
DDIT3 DNA-damage-inducible transcript 3
DDIT4 DNA-damage-inducible transcript 4
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
DDX60 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60
EIF2AK2 eukaryotic translation initiation factor 2-alpha kinase 2
ERAP1 endoplasmic reticulum aminopeptidase 1
FAM129A family with sequence similarity 129, member A
FTH1 ferritin, heavy polypeptide 1
GBP1 guanylate binding protein 1, interferon-inducible
HCP5 HLA complex P5 (non-protein coding)
HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HLA-B major histocompatibility complex, class I, B
HLA-C major histocompatibility complex, class I, C
HLA-F major histocompatibility complex, class I, F
HLA-G major histocompatibility complex, class I, G
HMOX1 heme oxygenase 1
IFI16 interferon, gamma-inducible protein 16
IFI27 interferon, alpha-inducible protein 27
IFI35 interferon-induced protein 35
IFI44 interferon-induced protein 44
IFI44L interferon-induced protein 44-like
IFI6 interferon, alpha-inducible protein 6
IFIH1 interferon induced with helicase C domain 1
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IFIT3 interferon-induced protein with tetratricopeptide repeats 3
IFIT5 interferon-induced protein with tetratricopeptide repeats 5
IFITM1 interferon induced transmembrane protein 1
IRF7 interferon regulatory factor 7
IRF9 interferon regulatory factor 9
ISG15 ISG15 ubiquitin-like modifier
ISG20 interferon stimulated exonuclease gene 20kDa
JADE2 jade family PHD finger 2
LAMP3 lysosomal-associated membrane protein 3
LAP3 leucine aminopeptidase 3
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
LY6E lymphocyte antigen 6 complex, locus E
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
MUC16 mucin 16, cell surface associated
MX1 MX dynamin-like GTPase 1
MX2 MX dynamin-like GTPase 2
MYOF myoferlin
NMI N-myc (and STAT) interactor
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa
OAS2 2'-5'-oligoadenylate synthetase 2, 69/71kDa
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa
OASL 2'-5'-oligoadenylate synthetase-like
PARP12 poly (ADP-ribose) polymerase family, member 12
PERP PERP, TP53 apoptosis effector
PLEKHA5 pleckstrin homology domain containing, family A member 5
PLSCR1 phospholipid scramblase 1
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8
PSMB9 proteasome (prosome, macropain) subunit, beta type, 9
RSAD2 radical S-adenosyl methionine domain containing 2
RTP4 receptor (chemosensory) transporter protein 4
SAMD9 sterile alpha motif domain containing 9
SERP1 stress-associated endoplasmic reticulum protein 1
SERPING1 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1
SLC1A3 solute carrier family 1 (glial high affinity glutamate transporter), member 3
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
SP100 SP100 nuclear antigen
STAT1 signal transducer and activator of transcription 1, 91kDa
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
TMPRSS2 transmembrane protease, serine 2
TPD52L1 tumor protein D52-like 1
TRIM22 tripartite motif containing 22
UBE2L6 ubiquitin-conjugating enzyme E2L 6
USP18 ubiquitin specific peptidase 18
XAF1 XIAP associated factor 1
ZC3HAV1 zinc finger CCCH-type, antiviral 1

decreased expression

Symbol Name
ACTC1 actin, alpha, cardiac muscle 1
BMP2 bone morphogenetic protein 2
CALD1 caldesmon 1
CD151 CD151 molecule (Raph blood group)
CELF2 CUGBP, Elav-like family member 2
CNN3 calponin 3, acidic
CRIP1 cysteine-rich protein 1 (intestinal)
CRYAB crystallin, alpha B
CXADR coxsackie virus and adenovirus receptor
CXCL14 chemokine (C-X-C motif) ligand 14
DAG1 dystroglycan 1 (dystrophin-associated glycoprotein 1)
DHDDS dehydrodolichyl diphosphate synthase
ERBB2 erb-b2 receptor tyrosine kinase 2
FABP1 fatty acid binding protein 1, liver
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
MAGEA3 melanoma antigen family A3
MEF2C myocyte enhancer factor 2C
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
MYH3 myosin, heavy chain 3, skeletal muscle, embryonic
NEFL neurofilament, light polypeptide
NFIB nuclear factor I/B
PROM1 prominin 1
RGS2 regulator of G-protein signaling 2
S100P S100 calcium binding protein P
TNNC1 troponin C type 1 (slow)
TTN titin
VCAN versican
ZBTB18 zinc finger and BTB domain containing 18