BRD-A90451247_KU-60019_PC3_24_h_3.33_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

72 genes differentially expressed following the BRD-A90451247_KU-60019_PC3_24_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACTB actin, beta
ANXA3 annexin A3
ARG2 arginase 2
CAPG capping protein (actin filament), gelsolin-like
CCL4 chemokine (C-C motif) ligand 4
CDH17 cadherin 17, LI cadherin (liver-intestine)
CHST2 carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2
CNOT4 CCR4-NOT transcription complex, subunit 4
COCH cochlin
CXCL13 chemokine (C-X-C motif) ligand 13
E2F2 E2F transcription factor 2
EPN2 epsin 2
FLNA filamin A, alpha
GSTP1 glutathione S-transferase pi 1
HBB hemoglobin, beta
HNRNPH1 heterogeneous nuclear ribonucleoprotein H1 (H)
IFITM1 interferon induced transmembrane protein 1
IGHM immunoglobulin heavy constant mu
IL1B interleukin 1, beta
KCNK1 potassium channel, two pore domain subfamily K, member 1
LGALS3 lectin, galactoside-binding, soluble, 3
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MAN2A1 mannosidase, alpha, class 2A, member 1
MS4A1 membrane-spanning 4-domains, subfamily A, member 1
NEFH neurofilament, heavy polypeptide
OLFM4 olfactomedin 4
PACSIN3 protein kinase C and casein kinase substrate in neurons 3
PTN pleiotrophin
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans)
SEPP1 selenoprotein P, plasma, 1
SFN stratifin
SIRT3 sirtuin 3
SLC25A36 solute carrier family 25 (pyrimidine nucleotide carrier), member 36
SLC26A3 solute carrier family 26 (anion exchanger), member 3
SPOCK1 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1
STK26 serine/threonine protein kinase 26
TSPYL5 TSPY-like 5
TUBB2A tubulin, beta 2A class IIa
TUBB2B tubulin, beta 2B class IIb
TXNIP thioredoxin interacting protein
YTHDF1 YTH N(6)-methyladenosine RNA binding protein 1
ZFP36L1 ZFP36 ring finger protein-like 1

decreased expression

Symbol Name
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide
BEX1 brain expressed, X-linked 1
C3 complement component 3
C7 complement component 7
CADM1 cell adhesion molecule 1
CCR2 chemokine (C-C motif) receptor 2
CFH complement factor H
EMX2 empty spiracles homeobox 2
FABP4 fatty acid binding protein 4, adipocyte
FCER1A Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide
GPX3 glutathione peroxidase 3
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
LAMB1 laminin, beta 1
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
MX2 MX dynamin-like GTPase 2
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8
PTGIS prostaglandin I2 (prostacyclin) synthase
S100A8 S100 calcium binding protein A8
S100A9 S100 calcium binding protein A9
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
TBC1D8 TBC1 domain family, member 8 (with GRAM domain)
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
THBS2 thrombospondin 2
TOMM70A translocase of outer mitochondrial membrane 70 homolog A (S. cerevisiae)
WISP2 WNT1 inducible signaling pathway protein 2