BRD-A90451247_KU-60019_HCC515_24_h_3.33_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

51 genes differentially expressed following the BRD-A90451247_KU-60019_HCC515_24_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
CAPG capping protein (actin filament), gelsolin-like
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CTGF connective tissue growth factor
CTSB cathepsin B
CTSD cathepsin D
CTSL cathepsin L
CXCL13 chemokine (C-X-C motif) ligand 13
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
FTH1 ferritin, heavy polypeptide 1
GNPDA1 glucosamine-6-phosphate deaminase 1
GPNMB glycoprotein (transmembrane) nmb
HMOX1 heme oxygenase 1
LGALS3 lectin, galactoside-binding, soluble, 3
PHLDA2 pleckstrin homology-like domain, family A, member 2
RGCC regulator of cell cycle
SCNN1A sodium channel, non voltage gated 1 alpha subunit
SPP1 secreted phosphoprotein 1
SQSTM1 sequestosome 1
THSD7A thrombospondin, type I, domain containing 7A
UGDH UDP-glucose 6-dehydrogenase
VAT1 vesicle amine transport 1
XIST X inactive specific transcript (non-protein coding)

decreased expression

Symbol Name
AKAP12 A kinase (PRKA) anchor protein 12
CLC Charcot-Leyden crystal galectin
CLDN18 claudin 18
CRLF1 cytokine receptor-like factor 1
DDX10 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10
DHRS2 dehydrogenase/reductase (SDR family) member 2
FHL1 four and a half LIM domains 1
HIST1H2BG histone cluster 1, H2bg
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HPRT1 hypoxanthine phosphoribosyltransferase 1
ITGA6 integrin, alpha 6
KLF2 Kruppel-like factor 2
LPAR6 lysophosphatidic acid receptor 6
ME2 malic enzyme 2, NAD(+)-dependent, mitochondrial
MN1 meningioma (disrupted in balanced translocation) 1
MYH11 myosin, heavy chain 11, smooth muscle
ODC1 ornithine decarboxylase 1
POLG2 polymerase (DNA directed), gamma 2, accessory subunit
PRDX4 peroxiredoxin 4
PRKCH protein kinase C, eta
RBP1 retinol binding protein 1, cellular
RGS2 regulator of G-protein signaling 2
RRAGD Ras-related GTP binding D
SOX9 SRY (sex determining region Y)-box 9
SSFA2 sperm specific antigen 2
TESC tescalcin
TFF1 trefoil factor 1
TKTL1 transketolase-like 1