BRD-A90451247_KU-60019_HCC515_24_h_1.11_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

63 genes differentially expressed following the BRD-A90451247_KU-60019_HCC515_24_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADO 2-aminoethanethiol (cysteamine) dioxygenase
ALCAM activated leukocyte cell adhesion molecule
ALDH5A1 aldehyde dehydrogenase 5 family, member A1
AQP3 aquaporin 3 (Gill blood group)
AZGP1 alpha-2-glycoprotein 1, zinc-binding
CTSL cathepsin L
CXCL8 chemokine (C-X-C motif) ligand 8
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic)
EZR ezrin
GDF15 growth differentiation factor 15
HBB hemoglobin, beta
HOMER3 homer scaffolding protein 3
KDM5D lysine (K)-specific demethylase 5D
LAMP2 lysosomal-associated membrane protein 2
LGALS1 lectin, galactoside-binding, soluble, 1
LIMCH1 LIM and calponin homology domains 1
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae)
MBNL2 muscleblind-like splicing regulator 2
MYO6 myosin VI
PLIN2 perilipin 2
RGCC regulator of cell cycle
RPS4Y1 ribosomal protein S4, Y-linked 1
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans)
SLC39A8 solute carrier family 39 (zinc transporter), member 8
SQSTM1 sequestosome 1
SRGN serglycin
STX3 syntaxin 3
TPD52 tumor protein D52
TTC39A tetratricopeptide repeat domain 39A
TUBA1A tubulin, alpha 1a
UGDH UDP-glucose 6-dehydrogenase
VAT1 vesicle amine transport 1

decreased expression

Symbol Name
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide
AKT3 v-akt murine thymoma viral oncogene homolog 3
CDC42EP3 CDC42 effector protein (Rho GTPase binding) 3
CHGB chromogranin B
DMD dystrophin
FAM69A family with sequence similarity 69, member A
FHL1 four and a half LIM domains 1
GBP1 guanylate binding protein 1, interferon-inducible
GDI2 GDP dissociation inhibitor 2
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
IGF1 insulin-like growth factor 1 (somatomedin C)
IGHM immunoglobulin heavy constant mu
ITM2A integral membrane protein 2A
KRT14 keratin 14, type I
KRT17 keratin 17, type I
LTF lactotransferrin
MAGEA12 melanoma antigen family A12
MAGEA3 melanoma antigen family A3
MAGEA6 melanoma antigen family A6
MAN1C1 mannosidase, alpha, class 1C, member 1
RPS11 ribosomal protein S11
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SFRP1 secreted frizzled-related protein 1
SMC1A structural maintenance of chromosomes 1A
UAP1 UDP-N-acetylglucosamine pyrophosphorylase 1
XIST X inactive specific transcript (non-protein coding)