BRD-A90451247_KU-60019_HA1E_24_h_1.11_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

116 genes differentially expressed following the BRD-A90451247_KU-60019_HA1E_24_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1
ACKR3 atypical chemokine receptor 3
ALAS1 5'-aminolevulinate synthase 1
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial)
ALDH3A2 aldehyde dehydrogenase 3 family, member A2
ASS1 argininosuccinate synthase 1
C1ORF106 chromosome 1 open reading frame 106
C3AR1 complement component 3a receptor 1
CALML3 calmodulin-like 3
CD24 CD24 molecule
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CEBPD CCAAT/enhancer binding protein (C/EBP), delta
CECR1 cat eye syndrome chromosome region, candidate 1
CELF2 CUGBP, Elav-like family member 2
CES2 carboxylesterase 2
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CLEC2B C-type lectin domain family 2, member B
COL1A2 collagen, type I, alpha 2
COL3A1 collagen, type III, alpha 1
COL5A1 collagen, type V, alpha 1
COLEC12 collectin sub-family member 12
CORO1A coronin, actin binding protein, 1A
CREB1 cAMP responsive element binding protein 1
CTSS cathepsin S
CXCR4 chemokine (C-X-C motif) receptor 4
DAPK1 death-associated protein kinase 1
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
DSP desmoplakin
EPB41L3 erythrocyte membrane protein band 4.1-like 3
FAM198B family with sequence similarity 198, member B
FAR2 fatty acyl CoA reductase 2
FCGBP Fc fragment of IgG binding protein
FGFR3 fibroblast growth factor receptor 3
FOXN3 forkhead box N3
FRS2 fibroblast growth factor receptor substrate 2
FRZB frizzled-related protein
FZD5 frizzled class receptor 5
GALC galactosylceramidase
GPNMB glycoprotein (transmembrane) nmb
GPR183 G protein-coupled receptor 183
HCAR3 hydroxycarboxylic acid receptor 3
IGHD immunoglobulin heavy constant delta
IGHM immunoglobulin heavy constant mu
IGKV1-5 immunoglobulin kappa variable 1-5
IGKV3-20 immunoglobulin kappa variable 3-20
IGKV4-1 immunoglobulin kappa variable 4-1
IGL immunoglobulin lambda locus
IGLJ3 immunoglobulin lambda joining 3
IL13RA2 interleukin 13 receptor, alpha 2
IMPA2 inositol(myo)-1(or 4)-monophosphatase 2
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
KDM5D lysine (K)-specific demethylase 5D
KLF4 Kruppel-like factor 4 (gut)
KLF9 Kruppel-like factor 9
KLHDC2 kelch domain containing 2
KRT18 keratin 18, type I
LAMP3 lysosomal-associated membrane protein 3
LAPTM4B lysosomal protein transmembrane 4 beta
LOX lysyl oxidase
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MFAP5 microfibrillar associated protein 5
NCF4 neutrophil cytosolic factor 4, 40kDa
OLFM4 olfactomedin 4
OXA1L oxidase (cytochrome c) assembly 1-like
PLAC8 placenta-specific 8
PLBD1 phospholipase B domain containing 1
PLS1 plastin 1
POSTN periostin, osteoblast specific factor
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform
PTPRC protein tyrosine phosphatase, receptor type, C
RCBTB2 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
RGCC regulator of cell cycle
RPS4Y1 ribosomal protein S4, Y-linked 1
RSAD2 radical S-adenosyl methionine domain containing 2
SAMSN1 SAM domain, SH3 domain and nuclear localization signals 1
SCG2 secretogranin II
SDC1 syndecan 1
SLAMF7 SLAM family member 7
SNX7 sorting nexin 7
SPRR1A small proline-rich protein 1A
SST somatostatin
STAT1 signal transducer and activator of transcription 1, 91kDa
SULF1 sulfatase 1
TGFB3 transforming growth factor, beta 3
TIMP2 TIMP metallopeptidase inhibitor 2
TMEM176B transmembrane protein 176B
TRAPPC6A trafficking protein particle complex 6A
VPS28 vacuolar protein sorting 28 homolog (S. cerevisiae)
ZFAND5 zinc finger, AN1-type domain 5
ZFP36 ZFP36 ring finger protein
ZIC1 Zic family member 1
ZNF318 zinc finger protein 318

decreased expression

Symbol Name
AGTR1 angiotensin II receptor, type 1
AREG amphiregulin
C7 complement component 7
DDX10 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10
LIMS1 LIM and senescent cell antigen-like domains 1
LTF lactotransferrin
MBD2 methyl-CpG binding domain protein 2
MCAM melanoma cell adhesion molecule
NKX3-1 NK3 homeobox 1
NPY neuropeptide Y
NPY1R neuropeptide Y receptor Y1
NR2F2 nuclear receptor subfamily 2, group F, member 2
PAN2 PAN2 poly(A) specific ribonuclease subunit
PDLIM1 PDZ and LIM domain 1
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PIP prolactin-induced protein
PRPS2 phosphoribosyl pyrophosphate synthetase 2
SACS sacsin molecular chaperone
SIGLEC15 sialic acid binding Ig-like lectin 15
TMEM100 transmembrane protein 100
TNC tenascin C
WDR7 WD repeat domain 7
XIST X inactive specific transcript (non-protein coding)