BRD-A90451247_KU-60019_HA1E_24_h_0.04_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

111 genes differentially expressed following the BRD-A90451247_KU-60019_HA1E_24_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACD adrenocortical dysplasia homolog (mouse)
ALDH1A3 aldehyde dehydrogenase 1 family, member A3
ANKRD36B ankyrin repeat domain 36B
ASS1 argininosuccinate synthase 1
BCAS1 breast carcinoma amplified sequence 1
BPIFA1 BPI fold containing family A, member 1
BPTF bromodomain PHD finger transcription factor
CALM3 calmodulin 3 (phosphorylase kinase, delta)
CCL20 chemokine (C-C motif) ligand 20
CEMIP cell migration inducing protein, hyaluronan binding
CEP57 centrosomal protein 57kDa
CES1 carboxylesterase 1
CHST15 carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15
COL16A1 collagen, type XVI, alpha 1
COL5A1 collagen, type V, alpha 1
COL9A2 collagen, type IX, alpha 2
COL9A3 collagen, type IX, alpha 3
COLEC12 collectin sub-family member 12
CORO1A coronin, actin binding protein, 1A
CPD carboxypeptidase D
EXPH5 exophilin 5
FAM198B family with sequence similarity 198, member B
FGFR3 fibroblast growth factor receptor 3
GATA6 GATA binding protein 6
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HMGB3 high mobility group box 3
IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial
IGFBP4 insulin-like growth factor binding protein 4
IL1R1 interleukin 1 receptor, type I
IL1R2 interleukin 1 receptor, type II
ISLR immunoglobulin superfamily containing leucine-rich repeat
KCTD12 potassium channel tetramerization domain containing 12
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
KLF4 Kruppel-like factor 4 (gut)
KRT15 keratin 15, type I
LCN2 lipocalin 2
MAMLD1 mastermind-like domain containing 1
MDK midkine (neurite growth-promoting factor 2)
MMP12 matrix metallopeptidase 12
MUC4 mucin 4, cell surface associated
MUC5B mucin 5B, oligomeric mucus/gel-forming
NPEPL1 aminopeptidase-like 1
PAEP progestagen-associated endometrial protein
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PEG10 paternally expressed 10
PLLP plasmolipin
RCBTB2 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
RGCC regulator of cell cycle
S100P S100 calcium binding protein P
SDC2 syndecan 2
SLC38A1 solute carrier family 38, member 1
SNX7 sorting nexin 7
SORL1 sortilin-related receptor, L(DLR class) A repeats containing
SRRM2 serine/arginine repetitive matrix 2
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
STON1 stonin 1
STS steroid sulfatase (microsomal), isozyme S
TRIM2 tripartite motif containing 2
UCP2 uncoupling protein 2 (mitochondrial, proton carrier)
WFDC2 WAP four-disulfide core domain 2
WNT5A wingless-type MMTV integration site family, member 5A
XIST X inactive specific transcript (non-protein coding)

decreased expression

Symbol Name
ACTN1 actinin, alpha 1
AK4 adenylate kinase 4
ALCAM activated leukocyte cell adhesion molecule
ANXA3 annexin A3
ATP2B1 ATPase, Ca++ transporting, plasma membrane 1
BACE2 beta-site APP-cleaving enzyme 2
BST2 bone marrow stromal cell antigen 2
CA2 carbonic anhydrase II
CD47 CD47 molecule
CORO1C coronin, actin binding protein, 1C
CRYAB crystallin, alpha B
CSRP2 cysteine and glycine-rich protein 2
CXCL14 chemokine (C-X-C motif) ligand 14
CYB5A cytochrome b5 type A (microsomal)
DHRS7 dehydrogenase/reductase (SDR family) member 7
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3
DUSP5 dual specificity phosphatase 5
EIF5A eukaryotic translation initiation factor 5A
FLNA filamin A, alpha
GPM6B glycoprotein M6B
HBB hemoglobin, beta
HBD hemoglobin, delta
HMG20B high mobility group 20B
JMJD6 jumonji domain containing 6
KRT17 keratin 17, type I
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae)
LTF lactotransferrin
MCAM melanoma cell adhesion molecule
MOK MOK protein kinase
MT1H metallothionein 1H
NETO2 neuropilin (NRP) and tolloid (TLL)-like 2
NNMT nicotinamide N-methyltransferase
NPY1R neuropeptide Y receptor Y1
NUP62 nucleoporin 62kDa
PAWR PRKC, apoptosis, WT1, regulator
PDGFC platelet derived growth factor C
POLR3G polymerase (RNA) III (DNA directed) polypeptide G (32kD)
PRPF4 pre-mRNA processing factor 4
RND3 Rho family GTPase 3
SAP30 Sin3A-associated protein, 30kDa
SKAP2 src kinase associated phosphoprotein 2
SLC39A6 solute carrier family 39 (zinc transporter), member 6
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4
TMEM47 transmembrane protein 47
TNC tenascin C
TPD52L1 tumor protein D52-like 1
VCAM1 vascular cell adhesion molecule 1
ZNF274 zinc finger protein 274