BRD-A89208012_-666_HT29_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

107 genes differentially expressed following the BRD-A89208012_-666_HT29_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ALCAM activated leukocyte cell adhesion molecule
ARMCX2 armadillo repeat containing, X-linked 2
ARNT2 aryl-hydrocarbon receptor nuclear translocator 2
BTG2 BTG family, member 2
CD24 CD24 molecule
CDC42EP3 CDC42 effector protein (Rho GTPase binding) 3
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CFB complement factor B
CLIC4 chloride intracellular channel 4
CPB1 carboxypeptidase B1 (tissue)
DLK1 delta-like 1 homolog (Drosophila)
EIF5 eukaryotic translation initiation factor 5
FOLR1 folate receptor 1 (adult)
FRZB frizzled-related protein
GAB2 GRB2-associated binding protein 2
GATA3 GATA binding protein 3
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase)
GBP1 guanylate binding protein 1, interferon-inducible
GDF15 growth differentiation factor 15
GJA1 gap junction protein, alpha 1, 43kDa
GLIPR1 GLI pathogenesis-related 1
GPNMB glycoprotein (transmembrane) nmb
HBB hemoglobin, beta
HIST1H2AC histone cluster 1, H2ac
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
IGKC immunoglobulin kappa constant
IGL immunoglobulin lambda locus
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1
JCHAIN joining chain of multimeric IgA and IgM
LUM lumican
MAP7 microtubule-associated protein 7
MARCKS myristoylated alanine-rich protein kinase C substrate
MMP12 matrix metallopeptidase 12
MXRA7 matrix-remodelling associated 7
NARS2 asparaginyl-tRNA synthetase 2, mitochondrial (putative)
ORC1 origin recognition complex, subunit 1
PRUNE2 prune homolog 2 (Drosophila)
RARRES3 retinoic acid receptor responder (tazarotene induced) 3
RCAN2 regulator of calcineurin 2
RGCC regulator of cell cycle
RNF167 ring finger protein 167
RRAS2 related RAS viral (r-ras) oncogene homolog 2
SCGB1D2 secretoglobin, family 1D, member 2
SCGB2A1 secretoglobin, family 2A, member 1
SCPEP1 serine carboxypeptidase 1
SDC1 syndecan 1
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1
SFRP4 secreted frizzled-related protein 4
SLC5A3 solute carrier family 5 (sodium/myo-inositol cotransporter), member 3
SNAI2 snail family zinc finger 2
SNX13 sorting nexin 13
STX1A syntaxin 1A (brain)
TACSTD2 tumor-associated calcium signal transducer 2
TDO2 tryptophan 2,3-dioxygenase
TGM4 transglutaminase 4
TLE4 transducin-like enhancer of split 4
TMEM158 transmembrane protein 158 (gene/pseudogene)
TPD52L1 tumor protein D52-like 1
TSPAN8 tetraspanin 8
WNT5A wingless-type MMTV integration site family, member 5A
XIST X inactive specific transcript (non-protein coding)
ZBED5 zinc finger, BED-type containing 5
ZDHHC6 zinc finger, DHHC-type containing 6

decreased expression

Symbol Name
ABHD2 abhydrolase domain containing 2
CCDC86 coiled-coil domain containing 86
CLU clusterin
COL9A3 collagen, type IX, alpha 3
DPT dermatopontin
FABP4 fatty acid binding protein 4, adipocyte
FABP5 fatty acid binding protein 5 (psoriasis-associated)
FADS1 fatty acid desaturase 1
FOXF1 forkhead box F1
GMDS GDP-mannose 4,6-dehydratase
GPX3 glutathione peroxidase 3
HACD3 3-hydroxyacyl-CoA dehydratase 3
HMG20B high mobility group 20B
IL6ST interleukin 6 signal transducer
KDELR3 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3
KLF9 Kruppel-like factor 9
KRT4 keratin 4, type II
LPL lipoprotein lipase
LTBP1 latent transforming growth factor beta binding protein 1
LTBP3 latent transforming growth factor beta binding protein 3
MT1X metallothionein 1X
NOTCH2NL notch 2 N-terminal like
NPDC1 neural proliferation, differentiation and control, 1
PPP1R14B protein phosphatase 1, regulatory (inhibitor) subunit 14B
RPS4Y1 ribosomal protein S4, Y-linked 1
S100A11 S100 calcium binding protein A11
SELE selectin E
SET SET nuclear proto-oncogene
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3
SLC24A3 solute carrier family 24 (sodium/potassium/calcium exchanger), member 3
SLC27A2 solute carrier family 27 (fatty acid transporter), member 2
SLC39A4 solute carrier family 39 (zinc transporter), member 4
SULT1A1 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
SYNCRIP synaptotagmin binding, cytoplasmic RNA interacting protein
SYNGR3 synaptogyrin 3
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
THBS4 thrombospondin 4
TIMP4 TIMP metallopeptidase inhibitor 4
TLR4 toll-like receptor 4
TMEM100 transmembrane protein 100
TXNIP thioredoxin interacting protein
YME1L1 YME1-like 1 ATPase