BRD-A88282067_-666_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

47 genes differentially expressed following the BRD-A88282067_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase)
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
C1QA complement component 1, q subcomponent, A chain
C1QB complement component 1, q subcomponent, B chain
CD163 CD163 molecule
CP ceruloplasmin (ferroxidase)
CXCL10 chemokine (C-X-C motif) ligand 10
CXCL13 chemokine (C-X-C motif) ligand 13
CXCL9 chemokine (C-X-C motif) ligand 9
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
HIST1H1C histone cluster 1, H1c
HOPX HOP homeobox
IGHM immunoglobulin heavy constant mu
IL2RB interleukin 2 receptor, beta
IL32 interleukin 32
KRT14 keratin 14, type I
KRT16 keratin 16, type I
KRT17 keratin 17, type I
KRT6A keratin 6A, type II
KRT6B keratin 6B, type II
LYPD3 LY6/PLAUR domain containing 3
MAP7 microtubule-associated protein 7
RGS2 regulator of G-protein signaling 2
RNASE1 ribonuclease, RNase A family, 1 (pancreatic)
SEPP1 selenoprotein P, plasma, 1
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8
SPRR1B small proline-rich protein 1B
TMEM176A transmembrane protein 176A
TMEM176B transmembrane protein 176B

decreased expression

Symbol Name
ACVR1 activin A receptor, type I
ADD3 adducin 3 (gamma)
ADGRG6 adhesion G protein-coupled receptor G6
ATP2A3 ATPase, Ca++ transporting, ubiquitous
CCL20 chemokine (C-C motif) ligand 20
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2
EAPP E2F-associated phosphoprotein
EMP2 epithelial membrane protein 2
FAIM Fas apoptotic inhibitory molecule
GADD45B growth arrest and DNA-damage-inducible, beta
GPC3 glypican 3
HAT1 histone acetyltransferase 1
LEF1 lymphoid enhancer-binding factor 1
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila)
SOBP sine oculis binding protein homolog (Drosophila)
SPINK1 serine peptidase inhibitor, Kazal type 1