BRD-A87137733_GSK-690693_HS578T_3_h_0.04_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

106 genes differentially expressed following the BRD-A87137733_GSK-690693_HS578T_3_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5
ACSL5 acyl-CoA synthetase long-chain family member 5
ADGRG1 adhesion G protein-coupled receptor G1
AKR1C3 aldo-keto reductase family 1, member C3
AMDHD2 amidohydrolase domain containing 2
ANK3 ankyrin 3, node of Ranvier (ankyrin G)
ATP1B3 ATPase, Na+/K+ transporting, beta 3 polypeptide
ATP8A1 ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1
BIRC2 baculoviral IAP repeat containing 2
BLNK B-cell linker
CCP110 centriolar coiled coil protein 110kDa
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CRIP1 cysteine-rich protein 1 (intestinal)
CXADR coxsackie virus and adenovirus receptor
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1
ERBB4 erb-b2 receptor tyrosine kinase 4
FABP5 fatty acid binding protein 5 (psoriasis-associated)
FGFR2 fibroblast growth factor receptor 2
FHL1 four and a half LIM domains 1
GUSBP11 glucuronidase, beta pseudogene 11
GUSBP3 glucuronidase, beta pseudogene 3
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
IKZF1 IKAROS family zinc finger 1 (Ikaros)
IL1R1 interleukin 1 receptor, type I
JAM3 junctional adhesion molecule 3
JCHAIN joining chain of multimeric IgA and IgM
KIAA0485 uncharacterized LOC57235
KRT5 keratin 5, type II
LDLRAD4 low density lipoprotein receptor class A domain containing 4
LRMP lymphoid-restricted membrane protein
MAOB monoamine oxidase B
MAP2K6 mitogen-activated protein kinase kinase 6
METTL7A methyltransferase like 7A
MFAP5 microfibrillar associated protein 5
N4BP2L2 NEDD4 binding protein 2-like 2
NINJ2 ninjurin 2
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PNKP polynucleotide kinase 3'-phosphatase
PPAP2B phosphatidic acid phosphatase type 2B
PYCARD PYD and CARD domain containing
SDC1 syndecan 1
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6
SOX4 SRY (sex determining region Y)-box 4
SPOCK1 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1
USP7 ubiquitin specific peptidase 7 (herpes virus-associated)
ZNF264 zinc finger protein 264
ZNF331 zinc finger protein 331
ZNF451 zinc finger protein 451
ZNF551 zinc finger protein 551
ZNF586 zinc finger protein 586

decreased expression

Symbol Name
ANXA3 annexin A3
APOE apolipoprotein E
AREG amphiregulin
AZGP1 alpha-2-glycoprotein 1, zinc-binding
CCND1 cyclin D1
CCND2 cyclin D2
CDV3 CDV3 homolog (mouse)
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
CPD carboxypeptidase D
CXCL8 chemokine (C-X-C motif) ligand 8
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5
DDX21 DEAD (Asp-Glu-Ala-Asp) box helicase 21
DDX3X DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12
ELANE elastase, neutrophil expressed
EPHA2 EPH receptor A2
EREG epiregulin
ETV1 ets variant 1
F3 coagulation factor III (thromboplastin, tissue factor)
FAM129A family with sequence similarity 129, member A
FOSL1 FOS-like antigen 1
GBP1 guanylate binding protein 1, interferon-inducible
GSTM3 glutathione S-transferase mu 3 (brain)
HBEGF heparin-binding EGF-like growth factor
HMGA2 high mobility group AT-hook 2
IFRD2 interferon-related developmental regulator 2
JUN jun proto-oncogene
KRT18 keratin 18, type I
LIMA1 LIM domain and actin binding 1
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MCL1 myeloid cell leukemia 1
MEIS2 Meis homeobox 2
NRN1 neuritin 1
PFKP phosphofructokinase, platelet
PGK1 phosphoglycerate kinase 1
PHLDA1 pleckstrin homology-like domain, family A, member 1
PHLDA2 pleckstrin homology-like domain, family A, member 2
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
PLAUR plasminogen activator, urokinase receptor
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
PPIF peptidylprolyl isomerase F
PTGER4 prostaglandin E receptor 4 (subtype EP4)
PTHLH parathyroid hormone-like hormone
S100P S100 calcium binding protein P
SCG5 secretogranin V
SDC4 syndecan 4
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3
TARP TCR gamma alternate reading frame protein
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TLR4 toll-like receptor 4