BRD-A87137733_GSK-690693_HS578T_24_h_1.11_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

77 genes differentially expressed following the BRD-A87137733_GSK-690693_HS578T_24_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ASMTL acetylserotonin O-methyltransferase-like
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CLDN10 claudin 10
CTSA cathepsin A
CYFIP2 cytoplasmic FMR1 interacting protein 2
DAB2 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12
DUSP6 dual specificity phosphatase 6
FAM46A family with sequence similarity 46, member A
FOXO4 forkhead box O4
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
IRS2 insulin receptor substrate 2
KLF2 Kruppel-like factor 2
LAMB2 laminin, beta 2 (laminin S)
MAP7 microtubule-associated protein 7
MTSS1 metastasis suppressor 1
NGFRAP1 nerve growth factor receptor (TNFRSF16) associated protein 1
NNMT nicotinamide N-methyltransferase
P4HTM prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
PDZK1IP1 PDZK1 interacting protein 1
QPCT glutaminyl-peptide cyclotransferase
RAMP1 receptor (G protein-coupled) activity modifying protein 1
RBKS ribokinase
RPS4Y1 ribosomal protein S4, Y-linked 1
S100A9 S100 calcium binding protein A9
SOX4 SRY (sex determining region Y)-box 4
TACC2 transforming, acidic coiled-coil containing protein 2
TFF1 trefoil factor 1
TFF3 trefoil factor 3 (intestinal)
TM4SF1 transmembrane 4 L six family member 1
TSC22D1 TSC22 domain family, member 1
YPEL5 yippee-like 5 (Drosophila)

decreased expression

Symbol Name
AK4 adenylate kinase 4
ANP32E acidic (leucine-rich) nuclear phosphoprotein 32 family, member E
ANPEP alanyl (membrane) aminopeptidase
AP1S2 adaptor-related protein complex 1, sigma 2 subunit
CADM1 cell adhesion molecule 1
CDC20 cell division cycle 20
CDC6 cell division cycle 6
CENPU centromere protein U
CXCL10 chemokine (C-X-C motif) ligand 10
CXCL11 chemokine (C-X-C motif) ligand 11
CXCL9 chemokine (C-X-C motif) ligand 9
E2F2 E2F transcription factor 2
ENO1 enolase 1, (alpha)
FABP5 fatty acid binding protein 5 (psoriasis-associated)
FABP7 fatty acid binding protein 7, brain
FOXM1 forkhead box M1
GALE UDP-galactose-4-epimerase
GBP1 guanylate binding protein 1, interferon-inducible
GOLT1B golgi transport 1B
GPM6B glycoprotein M6B
IKZF1 IKAROS family zinc finger 1 (Ikaros)
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1
LMNB1 lamin B1
MCM4 minichromosome maintenance complex component 4
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
MMP12 matrix metallopeptidase 12
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1
MYBL2 v-myb avian myeloblastosis viral oncogene homolog-like 2
NLRP2 NLR family, pyrin domain containing 2
NUCKS1 nuclear casein kinase and cyclin-dependent kinase substrate 1
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
RECQL RecQ helicase-like
RFC2 replication factor C (activator 1) 2, 40kDa
RFC4 replication factor C (activator 1) 4, 37kDa
RRM1 ribonucleotide reductase M1
RRM2 ribonucleotide reductase M2
SFRP1 secreted frizzled-related protein 1
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3
TOP2A topoisomerase (DNA) II alpha 170kDa
TYMS thymidylate synthetase
WARS tryptophanyl-tRNA synthetase
XIST X inactive specific transcript (non-protein coding)
ZWINT ZW10 interacting kinetochore protein