BRD-A87137733_GSK-690693_BT20_3_h_1.11_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

36 genes differentially expressed following the BRD-A87137733_GSK-690693_BT20_3_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCA8 ATP-binding cassette, sub-family A (ABC1), member 8
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1
ALDH1A3 aldehyde dehydrogenase 1 family, member A3
ARID5B AT rich interactive domain 5B (MRF1-like)
ATF3 activating transcription factor 3
C10ORF10 chromosome 10 open reading frame 10
CCNG2 cyclin G2
CEBPD CCAAT/enhancer binding protein (C/EBP), delta
CHIC2 cysteine-rich hydrophobic domain 2
CXCL2 chemokine (C-X-C motif) ligand 2
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
ERBB3 erb-b2 receptor tyrosine kinase 3
FST follistatin
GATA3 GATA binding protein 3
KRT19 keratin 19, type I
KRT5 keratin 5, type II
MAN1A1 mannosidase, alpha, class 1A, member 1
METTL7A methyltransferase like 7A
PDGFD platelet derived growth factor D
PLAT plasminogen activator, tissue
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
SERPING1 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1
SFRP1 secreted frizzled-related protein 1
TACSTD2 tumor-associated calcium signal transducer 2
TGFBR3 transforming growth factor, beta receptor III
TUBA1A tubulin, alpha 1a

decreased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADM adrenomedullin
CALML4 calmodulin-like 4
CHN1 chimerin 1
GATA2 GATA binding protein 2
GCNT3 glucosaminyl (N-acetyl) transferase 3, mucin type
MMP3 matrix metallopeptidase 3
MSLN mesothelin
PRDX2 peroxiredoxin 2
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3