BRD-A86792397_-666_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

57 genes differentially expressed following the BRD-A86792397_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACSL3 acyl-CoA synthetase long-chain family member 3
AFF1 AF4/FMR2 family, member 1
AKAP8L A kinase (PRKA) anchor protein 8-like
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial)
BASP1 brain abundant, membrane attached signal protein 1
CAP2 CAP, adenylate cyclase-associated protein, 2 (yeast)
CAV1 caveolin 1, caveolae protein, 22kDa
CD44 CD44 molecule (Indian blood group)
CLGN calmegin
DACH1 dachshund family transcription factor 1
DCT dopachrome tautomerase
DST dystonin
EFNB2 ephrin-B2
FZD6 frizzled class receptor 6
G6PD glucose-6-phosphate dehydrogenase
HEG1 heart development protein with EGF-like domains 1
LDLR low density lipoprotein receptor
LGR5 leucine-rich repeat containing G protein-coupled receptor 5
MAPKAPK5 mitogen-activated protein kinase-activated protein kinase 5
MELK maternal embryonic leucine zipper kinase
MYOF myoferlin
NAV2 neuron navigator 2
PIEZO1 piezo-type mechanosensitive ion channel component 1
PPAP2B phosphatidic acid phosphatase type 2B
PPP1R15A protein phosphatase 1, regulatory subunit 15A
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
SLC38A1 solute carrier family 38, member 1
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SVIL supervillin
TCFL5 transcription factor-like 5 (basic helix-loop-helix)
TXNRD1 thioredoxin reductase 1

decreased expression

Symbol Name
A2M alpha-2-macroglobulin
ADAM28 ADAM metallopeptidase domain 28
ADIRF adipogenesis regulatory factor
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
ALDH5A1 aldehyde dehydrogenase 5 family, member A1
CCT2 chaperonin containing TCP1, subunit 2 (beta)
CD14 CD14 molecule
CD52 CD52 molecule
DCN decorin
FXYD3 FXYD domain containing ion transport regulator 3
GSTA1 glutathione S-transferase alpha 1
HAPLN1 hyaluronan and proteoglycan link protein 1
KRT19 keratin 19, type I
KRT23 keratin 23, type I
MMP7 matrix metallopeptidase 7
MMP9 matrix metallopeptidase 9
MT1X metallothionein 1X
MYRF myelin regulatory factor
POLR2I polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa
PON3 paraoxonase 3
RNASE1 ribonuclease, RNase A family, 1 (pancreatic)
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SPINK1 serine peptidase inhibitor, Kazal type 1