BRD-A85587465_MDL 72222_VCAP_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

63 genes differentially expressed following the BRD-A85587465_MDL 72222_VCAP_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ALOX5AP arachidonate 5-lipoxygenase-activating protein
ANXA1 annexin A1
AQP4 aquaporin 4
BBOX1 butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1
CA3 carbonic anhydrase III
CALR calreticulin
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
CNN3 calponin 3, acidic
DLK1 delta-like 1 homolog (Drosophila)
DPYD dihydropyrimidine dehydrogenase
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
FBN2 fibrillin 2
FN1 fibronectin 1
G0S2 G0/G1 switch 2
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase)
HOMER3 homer scaffolding protein 3
HOPX HOP homeobox
IL32 interleukin 32
LYZ lysozyme
NEB nebulin
PLBD1 phospholipase B domain containing 1
RGCC regulator of cell cycle
RGS2 regulator of G-protein signaling 2
SLN sarcolipin
THBS4 thrombospondin 4
VIM vimentin
XIST X inactive specific transcript (non-protein coding)
ZNF91 zinc finger protein 91

decreased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AGTR1 angiotensin II receptor, type 1
ALCAM activated leukocyte cell adhesion molecule
AQP3 aquaporin 3 (Gill blood group)
CANT1 calcium activated nucleotidase 1
CD81 CD81 molecule
CDK4 cyclin-dependent kinase 4
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
DPYSL2 dihydropyrimidinase-like 2
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
ETNK1 ethanolamine kinase 1
GPX2 glutathione peroxidase 2
GSN gelsolin
HACD2 3-hydroxyacyl-CoA dehydratase 2
KDM5D lysine (K)-specific demethylase 5D
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
MARCKS myristoylated alanine-rich protein kinase C substrate
MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase
NAAA N-acylethanolamine acid amidase
NPDC1 neural proliferation, differentiation and control, 1
PRR7 proline rich 7 (synaptic)
SLC27A2 solute carrier family 27 (fatty acid transporter), member 2
SLC39A6 solute carrier family 39 (zinc transporter), member 6
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5
SORD sorbitol dehydrogenase
STEAP1 six transmembrane epithelial antigen of the prostate 1
TFF3 trefoil factor 3 (intestinal)
THAP11 THAP domain containing 11
TSPAN13 tetraspanin 13
TSPAN8 tetraspanin 8
UBR7 ubiquitin protein ligase E3 component n-recognin 7 (putative)
UGDH UDP-glucose 6-dehydrogenase
USP9Y ubiquitin specific peptidase 9, Y-linked