BRD-A85587465_-666_MCF7_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

44 genes differentially expressed following the BRD-A85587465_-666_MCF7_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACAT2 acetyl-CoA acetyltransferase 2
CD58 CD58 molecule
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast)
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
COL1A1 collagen, type I, alpha 1
CSTA cystatin A (stefin A)
CXCL14 chemokine (C-X-C motif) ligand 14
DUSP6 dual specificity phosphatase 6
ENO2 enolase 2 (gamma, neuronal)
FADS1 fatty acid desaturase 1
FADS2 fatty acid desaturase 2
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)
HEPH hephaestin
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
HOMER1 homer scaffolding protein 1
HOPX HOP homeobox
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
IDI1 isopentenyl-diphosphate delta isomerase 1
IL32 interleukin 32
MSMO1 methylsterol monooxygenase 1
PRKCQ protein kinase C, theta
SAT1 spermidine/spermine N1-acetyltransferase 1
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SLC39A4 solute carrier family 39 (zinc transporter), member 4
TM4SF1 transmembrane 4 L six family member 1
VAV3 vav 3 guanine nucleotide exchange factor

decreased expression

Symbol Name
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide
AQP1 aquaporin 1 (Colton blood group)
CCT2 chaperonin containing TCP1, subunit 2 (beta)
CD81 CD81 molecule
DEFB1 defensin, beta 1
EPB41L3 erythrocyte membrane protein band 4.1-like 3
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1
HSPD1 heat shock 60kDa protein 1 (chaperonin)
LIMCH1 LIM and calponin homology domains 1
LPL lipoprotein lipase
MAP7 microtubule-associated protein 7
OLFML2A olfactomedin-like 2A
OSBPL1A oxysterol binding protein-like 1A
RGCC regulator of cell cycle
RNF167 ring finger protein 167
SPARCL1 SPARC-like 1 (hevin)
STEAP3 STEAP family member 3, metalloreductase