BRD-A82913781_-666_MCF7_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

65 genes differentially expressed following the BRD-A82913781_-666_MCF7_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3
AKAP12 A kinase (PRKA) anchor protein 12
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
ALCAM activated leukocyte cell adhesion molecule
ALDH3B1 aldehyde dehydrogenase 3 family, member B1
ASNS asparagine synthetase (glutamine-hydrolyzing)
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2
DDIT3 DNA-damage-inducible transcript 3
DDIT4 DNA-damage-inducible transcript 4
G0S2 G0/G1 switch 2
HMOX1 heme oxygenase 1
HSPA1A heat shock 70kDa protein 1A
IGFBP7 insulin-like growth factor binding protein 7
KRT7 keratin 7, type II
LAPTM4B lysosomal protein transmembrane 4 beta
MAP1B microtubule-associated protein 1B
MDK midkine (neurite growth-promoting factor 2)
MT1F metallothionein 1F
MT1X metallothionein 1X
NAV2 neuron navigator 2
NUPR1 nuclear protein, transcriptional regulator, 1
PGLS 6-phosphogluconolactonase
PHGDH phosphoglycerate dehydrogenase
PHYH phytanoyl-CoA 2-hydroxylase
PTX3 pentraxin 3, long
RARRES1 retinoic acid receptor responder (tazarotene induced) 1
RBP1 retinol binding protein 1, cellular
RHOBTB1 Rho-related BTB domain containing 1
S100P S100 calcium binding protein P
SCG5 secretogranin V
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SOX9 SRY (sex determining region Y)-box 9
STC2 stanniocalcin 2
TXNRD1 thioredoxin reductase 1
VIM vimentin
WARS tryptophanyl-tRNA synthetase

decreased expression

Symbol Name
CAV1 caveolin 1, caveolae protein, 22kDa
CAV2 caveolin 2
CCNA2 cyclin A2
CDKN2C cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)
CKB creatine kinase, brain
EBP emopamil binding protein (sterol isomerase)
ENO1 enolase 1, (alpha)
FASN fatty acid synthase
FEN1 flap structure-specific endonuclease 1
IL13RA1 interleukin 13 receptor, alpha 1
INSIG1 insulin induced gene 1
KIF14 kinesin family member 14
LDLR low density lipoprotein receptor
MAOA monoamine oxidase A
MAP7 microtubule-associated protein 7
MREG melanoregulin
MSMO1 methylsterol monooxygenase 1
PDLIM5 PDZ and LIM domain 5
PGAM1 phosphoglycerate mutase 1 (brain)
RRM2 ribonucleotide reductase M2
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SGK1 serum/glucocorticoid regulated kinase 1
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8
SPON1 spondin 1, extracellular matrix protein
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10