BRD-A82371568_-666_HT29_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

33 genes differentially expressed following the BRD-A82371568_-666_HT29_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
BTG3 BTG family, member 3
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
EGR3 early growth response 3
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
IL1R1 interleukin 1 receptor, type I
IL6ST interleukin 6 signal transducer
INPP1 inositol polyphosphate-1-phosphatase
REG1A regenerating islet-derived 1 alpha
TPD52L1 tumor protein D52-like 1

decreased expression

Symbol Name
AURKA aurora kinase A
BIRC5 baculoviral IAP repeat containing 5
BUB1 BUB1 mitotic checkpoint serine/threonine kinase
C1QA complement component 1, q subcomponent, A chain
C1QB complement component 1, q subcomponent, B chain
CCNB2 cyclin B2
CDC20 cell division cycle 20
CDC25B cell division cycle 25B
CDKN3 cyclin-dependent kinase inhibitor 3
DLGAP5 discs, large (Drosophila) homolog-associated protein 5
FAM13A family with sequence similarity 13, member A
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
HMMR hyaluronan-mediated motility receptor (RHAMM)
HOPX HOP homeobox
KIF20A kinesin family member 20A
LPL lipoprotein lipase
NRIP1 nuclear receptor interacting protein 1
PLK1 polo-like kinase 1
RARRES1 retinoic acid receptor responder (tazarotene induced) 1
RGS2 regulator of G-protein signaling 2
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
TOP2A topoisomerase (DNA) II alpha 170kDa
TOX3 TOX high mobility group box family member 3
UBE2C ubiquitin-conjugating enzyme E2C