BRD-A82307304_-666_PC3_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

81 genes differentially expressed following the BRD-A82307304_-666_PC3_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACKR3 atypical chemokine receptor 3
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide
AGR2 anterior gradient 2
ALDOC aldolase C, fructose-bisphosphate
APOD apolipoprotein D
AQP1 aquaporin 1 (Colton blood group)
AQP3 aquaporin 3 (Gill blood group)
ATF3 activating transcription factor 3
C8ORF4 chromosome 8 open reading frame 4
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CLIC3 chloride intracellular channel 3
CRIP1 cysteine-rich protein 1 (intestinal)
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
GRIA2 glutamate receptor, ionotropic, AMPA 2
HIST1H2BG histone cluster 1, H2bg
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
KDM5D lysine (K)-specific demethylase 5D
KLF6 Kruppel-like factor 6
LDLR low density lipoprotein receptor
MAP7 microtubule-associated protein 7
MGLL monoglyceride lipase
MMP1 matrix metallopeptidase 1
MS4A4A membrane-spanning 4-domains, subfamily A, member 4A
MSMB microseminoprotein, beta-
MUC5B mucin 5B, oligomeric mucus/gel-forming
PRKCD protein kinase C, delta
RABAC1 Rab acceptor 1 (prenylated)
RAP1GAP RAP1 GTPase activating protein
RNASE1 ribonuclease, RNase A family, 1 (pancreatic)
RPS4Y1 ribosomal protein S4, Y-linked 1
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans)
SEPP1 selenoprotein P, plasma, 1
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SFTPA2 surfactant protein A2
SFTPB surfactant protein B
SLC44A4 solute carrier family 44, member 4
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TFF1 trefoil factor 1
TFF3 trefoil factor 3 (intestinal)
TSC22D3 TSC22 domain family, member 3
TSPAN13 tetraspanin 13
TSPAN3 tetraspanin 3
TSPAN8 tetraspanin 8
WIPI1 WD repeat domain, phosphoinositide interacting 1

decreased expression

Symbol Name
ABCE1 ATP-binding cassette, sub-family E (OABP), member 1
CCND1 cyclin D1
CDC25A cell division cycle 25A
CDC6 cell division cycle 6
CENPU centromere protein U
CTPS1 CTP synthase 1
DTL denticleless E3 ubiquitin protein ligase homolog (Drosophila)
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
FEZ2 fasciculation and elongation protein zeta 2 (zygin II)
FST follistatin
GINS2 GINS complex subunit 2 (Psf2 homolog)
HEG1 heart development protein with EGF-like domains 1
IGFBP3 insulin-like growth factor binding protein 3
KIAA0101 KIAA0101
MCM2 minichromosome maintenance complex component 2
MCM3 minichromosome maintenance complex component 3
MCM6 minichromosome maintenance complex component 6
NOP56 NOP56 ribonucleoprotein
NQO1 NAD(P)H dehydrogenase, quinone 1
PCNA proliferating cell nuclear antigen
PLK2 polo-like kinase 2
PSPH phosphoserine phosphatase
PTGER3 prostaglandin E receptor 3 (subtype EP3)
RFC2 replication factor C (activator 1) 2, 40kDa
RFC3 replication factor C (activator 1) 3, 38kDa
RRM1 ribonucleotide reductase M1
RRM2 ribonucleotide reductase M2
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast)
TSPAN4 tetraspanin 4
TYMS thymidylate synthetase
XIST X inactive specific transcript (non-protein coding)
ZWINT ZW10 interacting kinetochore protein