BRD-A82197375_-666_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

91 genes differentially expressed following the BRD-A82197375_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABLIM1 actin binding LIM protein 1
ADCY7 adenylate cyclase 7
ADM adrenomedullin
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
ASNS asparagine synthetase (glutamine-hydrolyzing)
ATP6V1D ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D
C10ORF10 chromosome 10 open reading frame 10
C1QB complement component 1, q subcomponent, B chain
C3 complement component 3
CAMK2N1 calcium/calmodulin-dependent protein kinase II inhibitor 1
CD24 CD24 molecule
CD53 CD53 molecule
CLU clusterin
CP ceruloplasmin (ferroxidase)
CXCL11 chemokine (C-X-C motif) ligand 11
CXCL13 chemokine (C-X-C motif) ligand 13
CXCL9 chemokine (C-X-C motif) ligand 9
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3
DUSP5 dual specificity phosphatase 5
ENO2 enolase 2 (gamma, neuronal)
FEZ1 fasciculation and elongation protein zeta 1 (zygin I)
FZD5 frizzled class receptor 5
GUSBP11 glucuronidase, beta pseudogene 11
HACD1 3-hydroxyacyl-CoA dehydratase 1
HILPDA hypoxia inducible lipid droplet-associated
HOPX HOP homeobox
IDO1 indoleamine 2,3-dioxygenase 1
IGHM immunoglobulin heavy constant mu
IGKV1-5 immunoglobulin kappa variable 1-5
IGKV4-1 immunoglobulin kappa variable 4-1
IGLL3P immunoglobulin lambda-like polypeptide 3, pseudogene
IGLV2-23 immunoglobulin lambda variable 2-23
IKZF1 IKAROS family zinc finger 1 (Ikaros)
ITGA6 integrin, alpha 6
KDM5D lysine (K)-specific demethylase 5D
MAPKAPK5 mitogen-activated protein kinase-activated protein kinase 5
NRIP1 nuclear receptor interacting protein 1
NUPR1 nuclear protein, transcriptional regulator, 1
NXN nucleoredoxin
PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1
PPAP2B phosphatidic acid phosphatase type 2B
PPL periplakin
RAB4A RAB4A, member RAS oncogene family
RBPMS RNA binding protein with multiple splicing
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1
SLC38A1 solute carrier family 38, member 1
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
TNFRSF21 tumor necrosis factor receptor superfamily, member 21
TOX3 TOX high mobility group box family member 3
TRIM36 tripartite motif containing 36
XAF1 XIAP associated factor 1

decreased expression

Symbol Name
ADD3 adducin 3 (gamma)
ALDOB aldolase B, fructose-bisphosphate
ANPEP alanyl (membrane) aminopeptidase
CALB1 calbindin 1, 28kDa
CD1E CD1e molecule
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CPE carboxypeptidase E
CREM cAMP responsive element modulator
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1
CST7 cystatin F (leukocystatin)
CXCL5 chemokine (C-X-C motif) ligand 5
CYBA cytochrome b-245, alpha polypeptide
EXOSC4 exosome component 4
FABP5 fatty acid binding protein 5 (psoriasis-associated)
FBXL12 F-box and leucine-rich repeat protein 12
GOLT1B golgi transport 1B
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
HIST1H4C histone cluster 1, H4c
KDELR3 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3
LEPROTL1 leptin receptor overlapping transcript-like 1
MGP matrix Gla protein
MPO myeloperoxidase
MTUS1 microtubule associated tumor suppressor 1
NR4A2 nuclear receptor subfamily 4, group A, member 2
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
PCDH9 protocadherin 9
PDE4B phosphodiesterase 4B, cAMP-specific
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme
PRPF4 pre-mRNA processing factor 4
RARRES1 retinoic acid receptor responder (tazarotene induced) 1
RETN resistin
SLC7A7 solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
SRGN serglycin
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TFPI2 tissue factor pathway inhibitor 2
TSPYL5 TSPY-like 5
ZBTB18 zinc finger and BTB domain containing 18