BRD-A82096673_KUC103428N_A549_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

93 genes differentially expressed following the BRD-A82096673_KUC103428N_A549_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ANXA10 annexin A10
CST3 cystatin C
DDIT4 DNA-damage-inducible transcript 4
DDX10 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1
EPS8 epidermal growth factor receptor pathway substrate 8
EVI2A ecotropic viral integration site 2A
FOSL1 FOS-like antigen 1
GARS glycyl-tRNA synthetase
HNMT histamine N-methyltransferase
IGFBP7 insulin-like growth factor binding protein 7
IGHM immunoglobulin heavy constant mu
IGKV4-1 immunoglobulin kappa variable 4-1
INTS6 integrator complex subunit 6
KCNJ16 potassium channel, inwardly rectifying subfamily J, member 16
KCTD12 potassium channel tetramerization domain containing 12
KYNU kynureninase
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4
NNMT nicotinamide N-methyltransferase
OLFM4 olfactomedin 4
PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial)
PDLIM5 PDZ and LIM domain 5
PHGDH phosphoglycerate dehydrogenase
PLAT plasminogen activator, tissue
PRSS2 protease, serine, 2 (trypsin 2)
PSAT1 phosphoserine aminotransferase 1
RAP2A RAP2A, member of RAS oncogene family
S100A2 S100 calcium binding protein A2
S100P S100 calcium binding protein P
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SFN stratifin
SH3YL1 SH3 and SYLF domain containing 1
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SPINK4 serine peptidase inhibitor, Kazal type 4
SRC SRC proto-oncogene, non-receptor tyrosine kinase
TACSTD2 tumor-associated calcium signal transducer 2
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
TNFAIP8 tumor necrosis factor, alpha-induced protein 8
TSC22D3 TSC22 domain family, member 3
VEGFA vascular endothelial growth factor A
WWP1 WW domain containing E3 ubiquitin protein ligase 1
ZBTB38 zinc finger and BTB domain containing 38

decreased expression

Symbol Name
AK1 adenylate kinase 1
CCND3 cyclin D3
CD24 CD24 molecule
CD36 CD36 molecule (thrombospondin receptor)
CDKN2C cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)
CELF2 CUGBP, Elav-like family member 2
CKB creatine kinase, brain
COL5A2 collagen, type V, alpha 2
CP ceruloplasmin (ferroxidase)
CSRP2 cysteine and glycine-rich protein 2
CST6 cystatin E/M
DHCR24 24-dehydrocholesterol reductase
FABP4 fatty acid binding protein 4, adipocyte
FHOD3 formin homology 2 domain containing 3
FNBP1 formin binding protein 1
FZD7 frizzled class receptor 7
GAL galanin/GMAP prepropeptide
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HMGN3 high mobility group nucleosomal binding domain 3
IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial
IGL immunoglobulin lambda locus
KIF20A kinesin family member 20A
LSM14A LSM14A, SCD6 homolog A (S. cerevisiae)
LTF lactotransferrin
MEG3 maternally expressed 3 (non-protein coding)
MN1 meningioma (disrupted in balanced translocation) 1
MTUS1 microtubule associated tumor suppressor 1
NOV nephroblastoma overexpressed
PBK PDZ binding kinase
PEG10 paternally expressed 10
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
PFKM phosphofructokinase, muscle
PLAGL1 pleiomorphic adenoma gene-like 1
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta
PTCH1 patched 1
RAD23B RAD23 homolog B (S. cerevisiae)
RFX5 regulatory factor X, 5 (influences HLA class II expression)
RPL39L ribosomal protein L39-like
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SLC11A2 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2
SLC26A2 solute carrier family 26 (anion exchanger), member 2
SUPV3L1 suppressor of var1, 3-like 1 (S. cerevisiae)
TCF4 transcription factor 4
TFAP2B transcription factor AP-2 beta (activating enhancer binding protein 2 beta)
TPD52L1 tumor protein D52-like 1
TUBB6 tubulin, beta 6 class V
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
VTCN1 V-set domain containing T cell activation inhibitor 1