BRD-A81541225_-666_HT29_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

18 genes differentially expressed following the BRD-A81541225_-666_HT29_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AARS alanyl-tRNA synthetase
BTG1 B-cell translocation gene 1, anti-proliferative
C6ORF48 chromosome 6 open reading frame 48
CBS cystathionine-beta-synthase
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
DDIT4 DNA-damage-inducible transcript 4
FHL2 four and a half LIM domains 2
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NUPR1 nuclear protein, transcriptional regulator, 1
PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial)
PHGDH phosphoglycerate dehydrogenase
PSAT1 phosphoserine aminotransferase 1
SFRP1 secreted frizzled-related protein 1
SHMT2 serine hydroxymethyltransferase 2 (mitochondrial)
STC2 stanniocalcin 2
TSC22D3 TSC22 domain family, member 3

decreased expression

Symbol Name
ACTA2 actin, alpha 2, smooth muscle, aorta
ALDH3B2 aldehyde dehydrogenase 3 family, member B2