BRD-A81541225_-666_HA1E_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

39 genes differentially expressed following the BRD-A81541225_-666_HA1E_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABLIM1 actin binding LIM protein 1
AKR1C3 aldo-keto reductase family 1, member C3
ALCAM activated leukocyte cell adhesion molecule
AMDHD2 amidohydrolase domain containing 2
CBS cystathionine-beta-synthase
CD3D CD3d molecule, delta (CD3-TCR complex)
DDIT4 DNA-damage-inducible transcript 4
EZR ezrin
GDF15 growth differentiation factor 15
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HMOX1 heme oxygenase 1
ITM2A integral membrane protein 2A
MT1E metallothionein 1E
MT1G metallothionein 1G
MT1H metallothionein 1H
MT1M metallothionein 1M
MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase
MYC v-myc avian myelocytomatosis viral oncogene homolog
PAN2 PAN2 poly(A) specific ribonuclease subunit
PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial)
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
PTGER4 prostaglandin E receptor 4 (subtype EP4)
RBP1 retinol binding protein 1, cellular
RPS4Y1 ribosomal protein S4, Y-linked 1
RRP8 ribosomal RNA processing 8, methyltransferase, homolog (yeast)
S100A2 S100 calcium binding protein A2
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
TNFAIP8 tumor necrosis factor, alpha-induced protein 8
TRBC1 T cell receptor beta constant 1

decreased expression

Symbol Name
ANKRD10 ankyrin repeat domain 10
FCGR3B Fc fragment of IgG, low affinity IIIb, receptor (CD16b)
PEG10 paternally expressed 10
PLXNC1 plexin C1
S100A9 S100 calcium binding protein A9
TDO2 tryptophan 2,3-dioxygenase
VNN1 vanin 1