BRD-A81530502_8009-7630_PC3_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

119 genes differentially expressed following the BRD-A81530502_8009-7630_PC3_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABHD4 abhydrolase domain containing 4
ACKR3 atypical chemokine receptor 3
ATF3 activating transcription factor 3
ATF4 activating transcription factor 4
BMP2 bone morphogenetic protein 2
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3
BTG3 BTG family, member 3
CADM1 cell adhesion molecule 1
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CD9 CD9 molecule
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CHIC2 cysteine-rich hydrophobic domain 2
CLIC5 chloride intracellular channel 5
COL11A1 collagen, type XI, alpha 1
CSRP2 cysteine and glycine-rich protein 2
CXADR coxsackie virus and adenovirus receptor
CXCL8 chemokine (C-X-C motif) ligand 8
DAB2 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
DDIT4 DNA-damage-inducible transcript 4
DNAJC6 DnaJ (Hsp40) homolog, subfamily C, member 6
DSP desmoplakin
DUSP1 dual specificity phosphatase 1
EFNA1 ephrin-A1
EGFR epidermal growth factor receptor
ENO2 enolase 2 (gamma, neuronal)
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2
F11R F11 receptor
F3 coagulation factor III (thromboplastin, tissue factor)
FGFR3 fibroblast growth factor receptor 3
GADD45A growth arrest and DNA-damage-inducible, alpha
GBE1 glucan (1,4-alpha-), branching enzyme 1
GDF15 growth differentiation factor 15
GREM1 gremlin 1, DAN family BMP antagonist
HBEGF heparin-binding EGF-like growth factor
HILPDA hypoxia inducible lipid droplet-associated
HK2 hexokinase 2
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
INHBA inhibin, beta A
ITM2C integral membrane protein 2C
JAG1 jagged 1
JUNB jun B proto-oncogene
JUND jun D proto-oncogene
KCNK1 potassium channel, two pore domain subfamily K, member 1
KDM3A lysine (K)-specific demethylase 3A
KLF6 Kruppel-like factor 6
KRT6B keratin 6B, type II
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MAP1LC3B microtubule-associated protein 1 light chain 3 beta
MFAP2 microfibrillar-associated protein 2
MMP10 matrix metallopeptidase 10
MT1M metallothionein 1M
MXI1 MAX interactor 1, dimerization protein
MYC v-myc avian myelocytomatosis viral oncogene homolog
NDRG1 N-myc downstream regulated 1
NRG1 neuregulin 1
PALLD palladin, cytoskeletal associated protein
PCDH17 protocadherin 17
PDGFA platelet-derived growth factor alpha polypeptide
PELI1 pellino E3 ubiquitin protein ligase 1
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
PTP4A1 protein tyrosine phosphatase type IVA, member 1
PTPRC protein tyrosine phosphatase, receptor type, C
RAB11FIP1 RAB11 family interacting protein 1 (class I)
RGCC regulator of cell cycle
RIOK3 RIO kinase 3
SEC14L1 SEC14-like 1 (S. cerevisiae)
SERINC5 serine incorporator 5
SFN stratifin
SIK1 salt-inducible kinase 1
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3
SLC3A2 solute carrier family 3 (amino acid transporter heavy chain), member 2
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SQSTM1 sequestosome 1
TGFB2 transforming growth factor, beta 2
TIMP3 TIMP metallopeptidase inhibitor 3
TNIP1 TNFAIP3 interacting protein 1
TP53BP2 tumor protein p53 binding protein 2
TUFT1 tuftelin 1
VEGFA vascular endothelial growth factor A

decreased expression

Symbol Name
AIM1 absent in melanoma 1
ATP1A1 ATPase, Na+/K+ transporting, alpha 1 polypeptide
AURKA aurora kinase A
CA12 carbonic anhydrase XII
CCNA2 cyclin A2
CDC20 cell division cycle 20
CDC25B cell division cycle 25B
CENPA centromere protein A
CTSH cathepsin H
DCPS decapping enzyme, scavenger
DLGAP5 discs, large (Drosophila) homolog-associated protein 5
DUSP4 dual specificity phosphatase 4
EXOSC7 exosome component 7
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase)
HDDC2 HD domain containing 2
HIST1H4C histone cluster 1, H4c
HOXA10 homeobox A10
HOXC6 homeobox C6
KIF20A kinesin family member 20A
LMNB1 lamin B1
LOXL1 lysyl oxidase-like 1
MAP3K5 mitogen-activated protein kinase kinase kinase 5
NT5DC2 5'-nucleotidase domain containing 2
OBSL1 obscurin-like 1
PIP prolactin-induced protein
PLK1 polo-like kinase 1
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8
RARRES1 retinoic acid receptor responder (tazarotene induced) 1
RARRES3 retinoic acid receptor responder (tazarotene induced) 3
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
SFRP1 secreted frizzled-related protein 1
SORL1 sortilin-related receptor, L(DLR class) A repeats containing
SRSF7 serine/arginine-rich splicing factor 7
TMX4 thioredoxin-related transmembrane protein 4
TOP2A topoisomerase (DNA) II alpha 170kDa
TSEN2 TSEN2 tRNA splicing endonuclease subunit
TSPYL5 TSPY-like 5