BRD-A81530502_8009-7630_A375_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

98 genes differentially expressed following the BRD-A81530502_8009-7630_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADM adrenomedullin
AK4 adenylate kinase 4
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
ALDOC aldolase C, fructose-bisphosphate
BHLHE40 basic helix-loop-helix family, member e40
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like
C1ORF106 chromosome 1 open reading frame 106
CA2 carbonic anhydrase II
CCNG2 cyclin G2
CD24 CD24 molecule
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CEBPB CCAAT/enhancer binding protein (C/EBP), beta
CHIC2 cysteine-rich hydrophobic domain 2
CHST2 carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2
CP ceruloplasmin (ferroxidase)
CXCL8 chemokine (C-X-C motif) ligand 8
DDIT4 DNA-damage-inducible transcript 4
DUSP1 dual specificity phosphatase 1
DUSP6 dual specificity phosphatase 6
EEF1A2 eukaryotic translation elongation factor 1 alpha 2
EGR1 early growth response 1
FAM162A family with sequence similarity 162, member A
FAM60A family with sequence similarity 60, member A
FCER1A Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide
FEZ1 fasciculation and elongation protein zeta 1 (zygin I)
FN1 fibronectin 1
GDF15 growth differentiation factor 15
GLRX glutaredoxin (thioltransferase)
HILPDA hypoxia inducible lipid droplet-associated
HK2 hexokinase 2
HOXB6 homeobox B6
HS2ST1 heparan sulfate 2-O-sulfotransferase 1
IER2 immediate early response 2
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
IGFBP3 insulin-like growth factor binding protein 3
ISG20 interferon stimulated exonuclease gene 20kDa
JUN jun proto-oncogene
JUP junction plakoglobin
KDM3A lysine (K)-specific demethylase 3A
KDM7A lysine (K)-specific demethylase 7A
KRT23 keratin 23, type I
LOC100505650 uncharacterized LOC100505650
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MAGEA3 melanoma antigen family A3
MAGEA6 melanoma antigen family A6
MT1F metallothionein 1F
MT1HL1 metallothionein 1H-like 1
MT1X metallothionein 1X
MYC v-myc avian myelocytomatosis viral oncogene homolog
NDRG1 N-myc downstream regulated 1
NDUFA4L2 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2
NPIPB3 nuclear pore complex interacting protein family, member B3
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I
PDGFA platelet-derived growth factor alpha polypeptide
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
PFKP phosphofructokinase, platelet
PGK1 phosphoglycerate kinase 1
PHLDA2 pleckstrin homology-like domain, family A, member 2
PRAME preferentially expressed antigen in melanoma
PROM1 prominin 1
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
RGS2 regulator of G-protein signaling 2
S100A8 S100 calcium binding protein A8
SCGB2A1 secretoglobin, family 2A, member 1
SDC1 syndecan 1
SDC4 syndecan 4
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1
TMEM45A transmembrane protein 45A
TNIP1 TNFAIP3 interacting protein 1
TXNIP thioredoxin interacting protein
VEGFA vascular endothelial growth factor A

decreased expression

Symbol Name
ADIRF adipogenesis regulatory factor
AURKA aurora kinase A
CCNF cyclin F
CFB complement factor B
CHMP4A charged multivesicular body protein 4A
COL3A1 collagen, type III, alpha 1
CPVL carboxypeptidase, vitellogenic-like
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DACH1 dachshund family transcription factor 1
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
FUT8 fucosyltransferase 8 (alpha (1,6) fucosyltransferase)
GLIPR1 GLI pathogenesis-related 1
HSPA1A heat shock 70kDa protein 1A
HSPB8 heat shock 22kDa protein 8
MID1 midline 1
NAT1 N-acetyltransferase 1 (arylamine N-acetyltransferase)
PBK PDZ binding kinase
PCP4 Purkinje cell protein 4
PPARG peroxisome proliferator-activated receptor gamma
PTGDS prostaglandin D2 synthase 21kDa (brain)
PTGES prostaglandin E synthase
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
TMEM2 transmembrane protein 2