BRD-A81282034_-666_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

110 genes differentially expressed following the BRD-A81282034_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group)
ABHD4 abhydrolase domain containing 4
ADGRG2 adhesion G protein-coupled receptor G2
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
AKR1C3 aldo-keto reductase family 1, member C3
ALDH3A1 aldehyde dehydrogenase 3 family, member A1
ASNS asparagine synthetase (glutamine-hydrolyzing)
ATP2B1 ATPase, Ca++ transporting, plasma membrane 1
BTG1 B-cell translocation gene 1, anti-proliferative
CA12 carbonic anhydrase XII
CBR3 carbonyl reductase 3
CCND2 cyclin D2
CD163 CD163 molecule
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CRISP3 cysteine-rich secretory protein 3
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
DUSP5 dual specificity phosphatase 5
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic)
FOSL1 FOS-like antigen 1
FOXO1 forkhead box O1
G6PD glucose-6-phosphate dehydrogenase
GARS glycyl-tRNA synthetase
GCLC glutamate-cysteine ligase, catalytic subunit
GCLM glutamate-cysteine ligase, modifier subunit
GNG11 guanine nucleotide binding protein (G protein), gamma 11
HMOX1 heme oxygenase 1
IL6ST interleukin 6 signal transducer
MAN1A1 mannosidase, alpha, class 1A, member 1
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
MSRB1 methionine sulfoxide reductase B1
NARFL nuclear prelamin A recognition factor-like
NQO1 NAD(P)H dehydrogenase, quinone 1
OPN3 opsin 3
PGD phosphogluconate dehydrogenase
PIR pirin (iron-binding nuclear protein)
PRKCB protein kinase C, beta
RHCG Rh family, C glycoprotein
RNF167 ring finger protein 167
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans)
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SORBS2 sorbin and SH3 domain containing 2
SULT1A1 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
TALDO1 transaldolase 1
TGFBI transforming growth factor, beta-induced, 68kDa
TKT transketolase
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A
TPD52L1 tumor protein D52-like 1
TRIM16 tripartite motif containing 16
TSKU tsukushi, small leucine rich proteoglycan
TSPAN7 tetraspanin 7
TXNRD1 thioredoxin reductase 1
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
WIF1 WNT inhibitory factor 1
WNT5A wingless-type MMTV integration site family, member 5A

decreased expression

Symbol Name
AKAP12 A kinase (PRKA) anchor protein 12
APOLD1 apolipoprotein L domain containing 1
AZGP1 alpha-2-glycoprotein 1, zinc-binding
C10ORF10 chromosome 10 open reading frame 10
CAPG capping protein (actin filament), gelsolin-like
CCNE2 cyclin E2
CD36 CD36 molecule (thrombospondin receptor)
CST1 cystatin SN
CTSH cathepsin H
DLK1 delta-like 1 homolog (Drosophila)
DPT dermatopontin
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
FAM63A family with sequence similarity 63, member A
FAR2 fatty acyl CoA reductase 2
GAGE3 G antigen 3
GAS1 growth arrest-specific 1
GLUL glutamate-ammonia ligase
GPC3 glypican 3
HES1 hes family bHLH transcription factor 1
HNMT histamine N-methyltransferase
IFI27 interferon, alpha-inducible protein 27
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IFITM3 interferon induced transmembrane protein 3
IQGAP1 IQ motif containing GTPase activating protein 1
KRT7 keratin 7, type II
LGALS1 lectin, galactoside-binding, soluble, 1
MAGEA3 melanoma antigen family A3
MAGEA6 melanoma antigen family A6
MEIS2 Meis homeobox 2
MT1E metallothionein 1E
MYBPC1 myosin binding protein C, slow type
NFIB nuclear factor I/B
NR4A2 nuclear receptor subfamily 4, group A, member 2
NREP neuronal regeneration related protein
PIP prolactin-induced protein
PLEKHM1 pleckstrin homology domain containing, family M (with RUN domain) member 1
POSTN periostin, osteoblast specific factor
RAPGEF5 Rap guanine nucleotide exchange factor (GEF) 5
RGS5 regulator of G-protein signaling 5
RIN2 Ras and Rab interactor 2
SCGB1D2 secretoglobin, family 1D, member 2
SCGB2A2 secretoglobin, family 2A, member 2
SHB Src homology 2 domain containing adaptor protein B
SNX7 sorting nexin 7
SOX4 SRY (sex determining region Y)-box 4
SOX9 SRY (sex determining region Y)-box 9
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
TFRC transferrin receptor
TUBA1A tubulin, alpha 1a
VCAN versican