BRD-A81177136_-666_HEPG2_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

101 genes differentially expressed following the BRD-A81177136_-666_HEPG2_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
ARMCX6 armadillo repeat containing, X-linked 6
ASNS asparagine synthetase (glutamine-hydrolyzing)
C2CD2 C2 calcium-dependent domain containing 2
CDC42BPA CDC42 binding protein kinase alpha (DMPK-like)
CHMP4A charged multivesicular body protein 4A
CPB1 carboxypeptidase B1 (tissue)
CREB3L2 cAMP responsive element binding protein 3-like 2
CRISP3 cysteine-rich secretory protein 3
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2
CTH cystathionine gamma-lyase
EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HMG20B high mobility group 20B
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
LDLR low density lipoprotein receptor
MAMLD1 mastermind-like domain containing 1
MTSS1 metastasis suppressor 1
NAV2 neuron navigator 2
PLA2G16 phospholipase A2, group XVI
PLAT plasminogen activator, tissue
PYCR1 pyrroline-5-carboxylate reductase 1
RBPMS RNA binding protein with multiple splicing
SCGB2A2 secretoglobin, family 2A, member 2
SLC16A6 solute carrier family 16, member 6
SLC24A3 solute carrier family 24 (sodium/potassium/calcium exchanger), member 3
SQLE squalene epoxidase
STC2 stanniocalcin 2
STK26 serine/threonine protein kinase 26
TBL1X transducin (beta)-like 1X-linked
TPSAB1 tryptase alpha/beta 1

decreased expression

Symbol Name
ADM adrenomedullin
ANXA1 annexin A1
APOE apolipoprotein E
ASPH aspartate beta-hydroxylase
ATP13A3 ATPase type 13A3
C6ORF62 chromosome 6 open reading frame 62
CA2 carbonic anhydrase II
CANX calnexin
CAPRIN1 cell cycle associated protein 1
CBFB core-binding factor, beta subunit
CDV3 CDV3 homolog (mouse)
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CLIC4 chloride intracellular channel 4
COPA coatomer protein complex, subunit alpha
CPD carboxypeptidase D
DDX3X DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked
DHX9 DEAH (Asp-Glu-Ala-His) box helicase 9
EIF2S3 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa
EIF5A eukaryotic translation initiation factor 5A
ELAVL1 ELAV like RNA binding protein 1
ENO1 enolase 1, (alpha)
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
ERLIN1 ER lipid raft associated 1
F2RL1 coagulation factor II (thrombin) receptor-like 1
FABP5 fatty acid binding protein 5 (psoriasis-associated)
FKBP5 FK506 binding protein 5
FN1 fibronectin 1
GJA1 gap junction protein, alpha 1, 43kDa
HACD3 3-hydroxyacyl-CoA dehydratase 3
HSPD1 heat shock 60kDa protein 1 (chaperonin)
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
IKZF1 IKAROS family zinc finger 1 (Ikaros)
IPO13 importin 13
ITGA6 integrin, alpha 6
KCTD12 potassium channel tetramerization domain containing 12
LAMA4 laminin, alpha 4
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
MAT2A methionine adenosyltransferase II, alpha
MCL1 myeloid cell leukemia 1
MOB1A MOB kinase activator 1A
MYO1B myosin IB
PICALM phosphatidylinositol binding clathrin assembly protein
PRKAR1A protein kinase, cAMP-dependent, regulatory, type I, alpha
PTBP1 polypyrimidine tract binding protein 1
RRM1 ribonucleotide reductase M1
SCARB2 scavenger receptor class B, member 2
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SEPP1 selenoprotein P, plasma, 1
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1
SLC39A8 solute carrier family 39 (zinc transporter), member 8
SPTBN1 spectrin, beta, non-erythrocytic 1
SRPR signal recognition particle receptor (docking protein)
SRSF1 serine/arginine-rich splicing factor 1
SRSF6 serine/arginine-rich splicing factor 6
STIP1 stress-induced phosphoprotein 1
TF transferrin
TFDP1 transcription factor Dp-1
TFRC transferrin receptor
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
THBS1 thrombospondin 1
TMEM70 transmembrane protein 70
TMPRSS2 transmembrane protease, serine 2
TMX1 thioredoxin-related transmembrane protein 1
TRAM1 translocation associated membrane protein 1
TWF1 twinfilin actin binding protein 1
WAC WW domain containing adaptor with coiled-coil
WDR1 WD repeat domain 1
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta