BRD-A80775386_GR-237_PC3_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

98 genes differentially expressed following the BRD-A80775386_GR-237_PC3_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AARS alanyl-tRNA synthetase
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1
ACKR3 atypical chemokine receptor 3
AHR aryl hydrocarbon receptor
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
AMIGO2 adhesion molecule with Ig-like domain 2
APOD apolipoprotein D
ARF4 ADP-ribosylation factor 4
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2
ARMCX3 armadillo repeat containing, X-linked 3
ASNS asparagine synthetase (glutamine-hydrolyzing)
CA12 carbonic anhydrase XII
CALU calumenin
CCPG1 cell cycle progression 1
CTH cystathionine gamma-lyase
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DDIT4 DNA-damage-inducible transcript 4
DFNA5 deafness, autosomal dominant 5
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9
EGFR epidermal growth factor receptor
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1
EPAS1 endothelial PAS domain protein 1
FEZ1 fasciculation and elongation protein zeta 1 (zygin I)
FOXO4 forkhead box O4
GADD45A growth arrest and DNA-damage-inducible, alpha
GARS glycyl-tRNA synthetase
GFPT1 glutamine--fructose-6-phosphate transaminase 1
GOLT1B golgi transport 1B
HDLBP high density lipoprotein binding protein
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HSPA13 heat shock protein 70kDa family, member 13
IGFBP3 insulin-like growth factor binding protein 3
ITGB4 integrin, beta 4
KDELR3 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3
KRT17 keratin 17, type I
KYNU kynureninase
LGALS3 lectin, galactoside-binding, soluble, 3
MARS methionyl-tRNA synthetase
MET MET proto-oncogene, receptor tyrosine kinase
MGLL monoglyceride lipase
MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NPC1 Niemann-Pick disease, type C1
NRIP1 nuclear receptor interacting protein 1
NUPR1 nuclear protein, transcriptional regulator, 1
PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial)
PHGDH phosphoglycerate dehydrogenase
PXDC1 PX domain containing 1
RAPGEF2 Rap guanine nucleotide exchange factor (GEF) 2
SARS seryl-tRNA synthetase
SAT1 spermidine/spermine N1-acetyltransferase 1
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SEC22B SEC22 vesicle trafficking protein homolog B (S. cerevisiae) (gene/pseudogene)
SEC24D SEC24 family member D
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans)
SERINC5 serine incorporator 5
SLC2A10 solute carrier family 2 (facilitated glucose transporter), member 10
SLC7A1 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5
SQSTM1 sequestosome 1
STC2 stanniocalcin 2
STXBP2 syntaxin binding protein 2
TRIB3 tribbles pseudokinase 3
WIPI1 WD repeat domain, phosphoinositide interacting 1
XBP1 X-box binding protein 1
XPOT exportin, tRNA

decreased expression

Symbol Name
CCNA2 cyclin A2
CD320 CD320 molecule
CDC25A cell division cycle 25A
DLGAP5 discs, large (Drosophila) homolog-associated protein 5
FAM46A family with sequence similarity 46, member A
FCER1A Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide
GAL galanin/GMAP prepropeptide
H2AFX H2A histone family, member X
HHEX hematopoietically expressed homeobox
HIST1H4C histone cluster 1, H4c
HN1 hematological and neurological expressed 1
HOXC6 homeobox C6
HS3ST1 heparan sulfate (glucosamine) 3-O-sulfotransferase 1
KIAA0101 KIAA0101
KIF20A kinesin family member 20A
LMNB1 lamin B1
LYN LYN proto-oncogene, Src family tyrosine kinase
NUSAP1 nucleolar and spindle associated protein 1
PLEKHJ1 pleckstrin homology domain containing, family J member 1
PLK1 polo-like kinase 1
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta
SORD sorbitol dehydrogenase
SOX4 SRY (sex determining region Y)-box 4
STMN1 stathmin 1
STRA13 stimulated by retinoic acid 13
TBX3 T-box 3
TIMM13 translocase of inner mitochondrial membrane 13 homolog (yeast)
TOP2A topoisomerase (DNA) II alpha 170kDa
TYMS thymidylate synthetase