BRD-A77824596_FLUOCINOLONE ACETONIDE_A375_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

138 genes differentially expressed following the BRD-A77824596_FLUOCINOLONE ACETONIDE_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AARS alanyl-tRNA synthetase
ADAM10 ADAM metallopeptidase domain 10
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase)
ARNT2 aryl-hydrocarbon receptor nuclear translocator 2
BASP1 brain abundant, membrane attached signal protein 1
BHLHE40 basic helix-loop-helix family, member e40
CALD1 caldesmon 1
CALM3 calmodulin 3 (phosphorylase kinase, delta)
CD24 CD24 molecule
CD40 CD40 molecule, TNF receptor superfamily member 5
CTNND1 catenin (cadherin-associated protein), delta 1
CXADR coxsackie virus and adenovirus receptor
CXCL13 chemokine (C-X-C motif) ligand 13
DBN1 drebrin 1
DDIT4 DNA-damage-inducible transcript 4
EHBP1 EH domain binding protein 1
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
ERBB3 erb-b2 receptor tyrosine kinase 3
FBXL12 F-box and leucine-rich repeat protein 12
FGFR2 fibroblast growth factor receptor 2
FLNA filamin A, alpha
FN1 fibronectin 1
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
IGFBP7 insulin-like growth factor binding protein 7
JADE2 jade family PHD finger 2
JAG1 jagged 1
KLF9 Kruppel-like factor 9
KRT13 keratin 13, type I
KRT15 keratin 15, type I
KRT7 keratin 7, type II
LAMA4 laminin, alpha 4
LAMB1 laminin, beta 1
LDLR low density lipoprotein receptor
MAOA monoamine oxidase A
MARCKS myristoylated alanine-rich protein kinase C substrate
MEST mesoderm specific transcript
MFN2 mitofusin 2
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
MME membrane metallo-endopeptidase
MT1E metallothionein 1E
MT1F metallothionein 1F
MT1X metallothionein 1X
MUC4 mucin 4, cell surface associated
NFIL3 nuclear factor, interleukin 3 regulated
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
OSBPL10 oxysterol binding protein-like 10
PDLIM5 PDZ and LIM domain 5
POU2AF1 POU class 2 associating factor 1
PTPRK protein tyrosine phosphatase, receptor type, K
RGS5 regulator of G-protein signaling 5
RPS4Y1 ribosomal protein S4, Y-linked 1
RTN2 reticulon 2
SFRP1 secreted frizzled-related protein 1
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
SORBS2 sorbin and SH3 domain containing 2
SOX11 SRY (sex determining region Y)-box 11
TFAP2B transcription factor AP-2 beta (activating enhancer binding protein 2 beta)
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
TIMP3 TIMP metallopeptidase inhibitor 3
TSC22D3 TSC22 domain family, member 3
ZFP36L2 ZFP36 ring finger protein-like 2

decreased expression

Symbol Name
ANXA1 annexin A1
AP3S1 adaptor-related protein complex 3, sigma 1 subunit
ARG1 arginase 1
ATP2B1 ATPase, Ca++ transporting, plasma membrane 1
ATP6V0E1 ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1
BBOX1 butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like
CCNE2 cyclin E2
CCNH cyclin H
CETN3 centrin, EF-hand protein, 3
CLDN3 claudin 3
CLGN calmegin
CRABP2 cellular retinoic acid binding protein 2
CSRP2 cysteine and glycine-rich protein 2
CXCL14 chemokine (C-X-C motif) ligand 14
CXCL8 chemokine (C-X-C motif) ligand 8
DACH1 dachshund family transcription factor 1
DHRS2 dehydrogenase/reductase (SDR family) member 2
DKK1 dickkopf WNT signaling pathway inhibitor 1
EFHD1 EF-hand domain family, member D1
ESR1 estrogen receptor 1
FAM129A family with sequence similarity 129, member A
FBLN5 fibulin 5
G0S2 G0/G1 switch 2
GALNT6 polypeptide N-acetylgalactosaminyltransferase 6
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase)
GCA grancalcin, EF-hand calcium binding protein
GGH gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase)
GSTM3 glutathione S-transferase mu 3 (brain)
HAL histidine ammonia-lyase
HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5
HIST1H4C histone cluster 1, H4c
HSDL2 hydroxysteroid dehydrogenase like 2
IER3 immediate early response 3
IFI27 interferon, alpha-inducible protein 27
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IGFBP3 insulin-like growth factor binding protein 3
LAGE3 L antigen family, member 3
LAMC2 laminin, gamma 2
LGALS3 lectin, galactoside-binding, soluble, 3
LYRM1 LYR motif containing 1
MAN1A1 mannosidase, alpha, class 1A, member 1
MBP myelin basic protein
MCUR1 mitochondrial calcium uniporter regulator 1
MFAP4 microfibrillar-associated protein 4
MOCS2 molybdenum cofactor synthesis 2
NGRN neugrin, neurite outgrowth associated
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa
PCOLCE2 procollagen C-endopeptidase enhancer 2
PCSK6 proprotein convertase subtilisin/kexin type 6
PHYH phytanoyl-CoA 2-hydroxylase
PIP prolactin-induced protein
PROM1 prominin 1
PRPS2 phosphoribosyl pyrophosphate synthetase 2
PTN pleiotrophin
RAB4A RAB4A, member RAS oncogene family
RAPGEF5 Rap guanine nucleotide exchange factor (GEF) 5
RGS2 regulator of G-protein signaling 2
RPL37A ribosomal protein L37a
RPS11 ribosomal protein S11
RRAGD Ras-related GTP binding D
S100A12 S100 calcium binding protein A12
SFN stratifin
SKP1 S-phase kinase-associated protein 1
SLC39A8 solute carrier family 39 (zinc transporter), member 8
SLPI secretory leukocyte peptidase inhibitor
SORL1 sortilin-related receptor, L(DLR class) A repeats containing
SPARCL1 SPARC-like 1 (hevin)
TARBP1 TAR (HIV-1) RNA binding protein 1
TEX30 testis expressed 30
TSPAN5 tetraspanin 5
TSPAN7 tetraspanin 7
TSPAN8 tetraspanin 8
TUFT1 tuftelin 1