BRD-A77467113_-666_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

52 genes differentially expressed following the BRD-A77467113_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADM adrenomedullin
AKR1C1 aldo-keto reductase family 1, member C1
ATF3 activating transcription factor 3
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
DDIT3 DNA-damage-inducible transcript 3
DDIT4 DNA-damage-inducible transcript 4
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
DUSP5 dual specificity phosphatase 5
EGR2 early growth response 2
FOSL1 FOS-like antigen 1
GADD45A growth arrest and DNA-damage-inducible, alpha
GCLM glutamate-cysteine ligase, modifier subunit
HBEGF heparin-binding EGF-like growth factor
HMOX1 heme oxygenase 1
HSPA1A heat shock 70kDa protein 1A
HSPA6 heat shock 70kDa protein 6 (HSP70B')
IL1R2 interleukin 1 receptor, type II
KLF4 Kruppel-like factor 4 (gut)
MYC v-myc avian myelocytomatosis viral oncogene homolog
NFIL3 nuclear factor, interleukin 3 regulated
NR0B1 nuclear receptor subfamily 0, group B, member 1
NR4A1 nuclear receptor subfamily 4, group A, member 1
PKP1 plakophilin 1
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid)
PPP1R15A protein phosphatase 1, regulatory subunit 15A
SIK1 salt-inducible kinase 1
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3
SORBS2 sorbin and SH3 domain containing 2
TBX3 T-box 3
TRIB1 tribbles pseudokinase 1
TXNRD1 thioredoxin reductase 1
ZEB2 zinc finger E-box binding homeobox 2
ZFP36 ZFP36 ring finger protein

decreased expression

Symbol Name
ARL6IP5 ADP-ribosylation factor-like 6 interacting protein 5
B3GNT1
CCNF cyclin F
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1
ERBB3 erb-b2 receptor tyrosine kinase 3
GINS1 GINS complex subunit 1 (Psf1 homolog)
LAPTM4B lysosomal protein transmembrane 4 beta
LGALS1 lectin, galactoside-binding, soluble, 1
MLEC malectin
MREG melanoregulin
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NUP85 nucleoporin 85kDa
PCNA proliferating cell nuclear antigen
PIK3C2B phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta
PLK1 polo-like kinase 1
PROM1 prominin 1
SEPHS1 selenophosphate synthetase 1
SOX4 SRY (sex determining region Y)-box 4