BRD-A77467113_-666_HT29_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

80 genes differentially expressed following the BRD-A77467113_-666_HT29_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADM adrenomedullin
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
AKR1C3 aldo-keto reductase family 1, member C3
CBR3 carbonyl reductase 3
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CEBPD CCAAT/enhancer binding protein (C/EBP), delta
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2
CTH cystathionine gamma-lyase
CTSL cathepsin L
DDIT3 DNA-damage-inducible transcript 3
DDIT4 DNA-damage-inducible transcript 4
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
DUSP5 dual specificity phosphatase 5
FOSL1 FOS-like antigen 1
FTH1 ferritin, heavy polypeptide 1
GABPB1 GA binding protein transcription factor, beta subunit 1
GCLC glutamate-cysteine ligase, catalytic subunit
GCLM glutamate-cysteine ligase, modifier subunit
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
HMOX1 heme oxygenase 1
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1
HSPA1A heat shock 70kDa protein 1A
HSPA6 heat shock 70kDa protein 6 (HSP70B')
HSPA8 heat shock 70kDa protein 8
HSPD1 heat shock 60kDa protein 1 (chaperonin)
HSPH1 heat shock 105kDa/110kDa protein 1
HTATIP2 HIV-1 Tat interactive protein 2, 30kDa
IER5 immediate early response 5
IFRD1 interferon-related developmental regulator 1
ISG20 interferon stimulated exonuclease gene 20kDa
JUN jun proto-oncogene
KRT6A keratin 6A, type II
LAMA3 laminin, alpha 3
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
MT1F metallothionein 1F
MT1G metallothionein 1G
MT1H metallothionein 1H
MT1HL1 metallothionein 1H-like 1
MT1M metallothionein 1M
MT1X metallothionein 1X
MT2A metallothionein 2A
MYC v-myc avian myelocytomatosis viral oncogene homolog
NAMPT nicotinamide phosphoribosyltransferase
PHLDA2 pleckstrin homology-like domain, family A, member 2
PIR pirin (iron-binding nuclear protein)
PLIN2 perilipin 2
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
SEH1L SEH1-like (S. cerevisiae)
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)
SLC3A2 solute carrier family 3 (amino acid transporter heavy chain), member 2
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SMAD3 SMAD family member 3
SPARCL1 SPARC-like 1 (hevin)
SQSTM1 sequestosome 1
TGFBI transforming growth factor, beta-induced, 68kDa
TNFAIP6 tumor necrosis factor, alpha-induced protein 6
TXNRD1 thioredoxin reductase 1
UPP1 uridine phosphorylase 1
VEGFA vascular endothelial growth factor A

decreased expression

Symbol Name
B3GNT1
CD200 CD200 molecule
CXADR coxsackie virus and adenovirus receptor
F2R coagulation factor II (thrombin) receptor
GATA2 GATA binding protein 2
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
MACF1 microtubule-actin crosslinking factor 1
MAGED1 melanoma antigen family D1
MEIS1 Meis homeobox 1
MXRA5 matrix-remodelling associated 5
NRIP1 nuclear receptor interacting protein 1
PEG10 paternally expressed 10
RGS2 regulator of G-protein signaling 2
SCNN1A sodium channel, non voltage gated 1 alpha subunit
SOX4 SRY (sex determining region Y)-box 4
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
TYRP1 tyrosinase-related protein 1