BRD-A77467113_-666_A375_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

71 genes differentially expressed following the BRD-A77467113_-666_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACKR3 atypical chemokine receptor 3
AKAP13 A kinase (PRKA) anchor protein 13
AQP1 aquaporin 1 (Colton blood group)
ATF3 activating transcription factor 3
BAG3 BCL2-associated athanogene 3
BHLHE40 basic helix-loop-helix family, member e40
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CFD complement factor D (adipsin)
DSP desmoplakin
DUSP1 dual specificity phosphatase 1
EGR1 early growth response 1
EGR3 early growth response 3
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1
FHL2 four and a half LIM domains 2
FOSB FBJ murine osteosarcoma viral oncogene homolog B
FRY furry homolog (Drosophila)
GADD45A growth arrest and DNA-damage-inducible, alpha
GADD45B growth arrest and DNA-damage-inducible, beta
GEM GTP binding protein overexpressed in skeletal muscle
HBB hemoglobin, beta
HCAR3 hydroxycarboxylic acid receptor 3
HSPA6 heat shock 70kDa protein 6 (HSP70B')
IFITM1 interferon induced transmembrane protein 1
INSIG1 insulin induced gene 1
JUN jun proto-oncogene
JUNB jun B proto-oncogene
KLF4 Kruppel-like factor 4 (gut)
KRT5 keratin 5, type II
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MUC5B mucin 5B, oligomeric mucus/gel-forming
MYC v-myc avian myelocytomatosis viral oncogene homolog
NAMPT nicotinamide phosphoribosyltransferase
NEFL neurofilament, light polypeptide
NR4A1 nuclear receptor subfamily 4, group A, member 1
OPN3 opsin 3
PDGFA platelet-derived growth factor alpha polypeptide
PELI1 pellino E3 ubiquitin protein ligase 1
RGS2 regulator of G-protein signaling 2
RHOB ras homolog family member B
S100A2 S100 calcium binding protein A2
S100A7 S100 calcium binding protein A7
S100A8 S100 calcium binding protein A8
S100A9 S100 calcium binding protein A9
SFN stratifin
SIK1 salt-inducible kinase 1
SLPI secretory leukocyte peptidase inhibitor
SOCS3 suppressor of cytokine signaling 3
SPRR1A small proline-rich protein 1A
TPSAB1 tryptase alpha/beta 1
TPSB2 tryptase beta 2 (gene/pseudogene)
TRIB1 tribbles pseudokinase 1
TRIB3 tribbles pseudokinase 3
XBP1 X-box binding protein 1
ZFP36 ZFP36 ring finger protein

decreased expression

Symbol Name
ADI1 acireductone dioxygenase 1
AGTR1 angiotensin II receptor, type 1
CCNA2 cyclin A2
CDC20 cell division cycle 20
CDK1 cyclin-dependent kinase 1
COX11 COX11 cytochrome c oxidase copper chaperone
IER3 immediate early response 3
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
MARCKS myristoylated alanine-rich protein kinase C substrate
MRPS16 mitochondrial ribosomal protein S16
NPY neuropeptide Y
PLK1 polo-like kinase 1
PSPH phosphoserine phosphatase
SRPX sushi-repeat containing protein, X-linked
TOP2A topoisomerase (DNA) II alpha 170kDa